Replication studies in various ethnic populations do not support the association of the HIF-2α SNP rs17039192 with knee osteoarthritis.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

10 citing papers in PubMed.

1. Remodeling Osteoarthritic Articular Cartilage under Hypoxic Conditions.International journal of molecular sciences · 2022
   Review
2. Role of the Hypoxia-Inducible Factor Pathway in Normal and Osteoarthritic Meniscus and in Mice after Destabilization of the Medial Meniscus.Cartilage · 2021
   Article
3. Role of Signal Transduction Pathways and Transcription Factors in Cartilage and Joint Diseases.International journal of molecular sciences · 2020
   Review
4. Transcriptional network systems in cartilage development and disease.Histochemistry and cell biology · 2018
   Review
5. Regulation of Cartilage Development and Diseases by Transcription Factors.Journal of bone metabolism · 2017
   Review
6. Association between EN1 rs4144782 and susceptibility of knee osteoarthritis: A case-control study.Oncotarget · 2017
   Article
7. Cartilage damage in osteoarthritis and rheumatoid arthritis--two unequal siblings.Nature reviews. Rheumatology · 2015
   Review
8. Update on basic and clinical aspects of osteoarthritis.Annals of translational medicine · 2015
   Article
9. Proteases involved in cartilage matrix degradation in osteoarthritis.Biochimica et biophysica acta · 2012
   Review
10. Cartilage biology in osteoarthritis--lessons from developmental biology.Nature reviews. Rheumatology · 2011
    Review

Corrections and comments

• Comment on
  Transcriptional regulation of endochondral ossification by HIF-2alpha during skeletal growth and osteoarthritis development.2010

Authors and funding

9 authors.

Funding

No grant is acknowledged in the PubMed record.

Abstract

PubMed holds no abstract for this paper.

Indexed as