Evidence map›Paper›PMID 21217125›Full record

ArticlePlant & cell physiology2011

ATTED-II updates: condition-specific gene coexpression to extend coexpression analyses and applications to a broad range of flowering plants.

Takeshi Obayashi, Kozo Nishida, Kota Kasahara, Kengo Kinoshita

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Article in Plant & cell physiology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 73 papers.

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73citing papers in PubMed
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3 · Its place in the literature

Who cites it

73 citing papers in PubMed.

  1. Article
  2. NetREx: Network-based Rice Expression Analysis Server for abiotic stress conditions.Database : the journal of biological databases and curation · 2022
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  11. Genome-wide analysis of cis-regulatory element structure and discovery of motif-driven gene co-expression networks in grapevine.DNA research : an international journal for rapid publication of reports on genes and genomes · 2017
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13 more citing papers are in PubMed but not listed here.

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5 · Who and what money

Authors and funding

4 authors.

Takeshi ObayashiGraduate School of Information Science, Tohoku University, 6-3-09, Aramaki-Aza-Aoba, Aoba-ku, Sendai, 980-8679 Japan. takeshi.obayashi@atted.jp
Kozo Nishida
Kota Kasahara
Kengo Kinoshita

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

ATTED-II (http://atted.jp) is a gene coexpression database for a wide variety of experimental designs, such as prioritizations of genes for functional identification and analyses of the regulatory relationships among genes. Here, we report updates of ATTED-II focusing on two new features: condition-specific coexpression and homologous coexpression with rice. To analyze a broad range of biological phenomena, it is important to collect data under many diverse experimental conditions, but the meaning of coexpression can become ambiguous under these conditions. One approach to overcome this difficulty is to calculate the coexpression for each set of conditions with a clear biological meaning. With this viewpoint, we prepared five sets of experimental conditions (tissue, abiotic stress, biotic stress, hormones and light conditions), and users can evaluate the coexpression by employing comparative gene lists and switchable gene networks. We also developed an interactive visualization system, using the Cytoscape web system, to improve the network representation. As the second update, rice coexpression is now available. The previous version of ATTED-II was specifically developed for Arabidopsis, and thus coexpression analyses for other useful plants have been difficult. To solve this problem, we extended ATTED-II by including comparison tables between Arabidopsis and rice. This representation will make it possible to analyze the conservation of coexpression among flowering plants. With the ability to investigate condition-specific coexpression and species conservation, ATTED-II can help researchers to clarify the functional and regulatory networks of genes in a broad array of plant species.

Indexed as

Databases, GeneticArabidopsisComputational BiologyGene Expression ProfilingGene Expression Regulation, PlantGene Regulatory NetworksOryza

Identifiers

PMID21217125
PMCPMC3037081

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.