Trial reportJournal of dentistry2011
The critical barrier to progress in dentine bonding with the etch-and-rinse technique.
Trial report in Journal of dentistry, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
32 citing papers in PubMed.
- Mapping water and monomer gradients in the adhesive/dentin interface with confocal micro-Raman imaging.Dental materials : official publication of the Academy of Dental Materials · 2025Article
- Comparative In Vitro Study of Sol-Gel-Derived Bioactive Glasses Incorporated into Dentin Adhesives: Effects on Remineralization and Mechanical Properties of Dentin.Journal of functional biomaterials · 2025Article
- The influence of neutral MDP-Na salt on dentin bond performance and remineralization potential of etch-&-rinse adhesive.BMC oral health · 2024Article
- Engineering Interfacial Integrity with Hydrolytic-Resistant, Self-Reinforcing Dentin Adhesive.International journal of molecular sciences · 2024Article
- Effect of different application strategies of universal adhesive used for immediate and delayed dentin sealing on the microtensile bond strength of self-adhesive resin cement to dentin with and without aging.Journal of clinical and experimental dentistry · 2023Article
- Mussel-inspired polymer with catechol and cationic Lys functionalities for dentin wet bonding.Materials today. Bio · 2023Article
- Insight into the development of versatile dentin bonding agents to increase the durability of the bonding interface.Frontiers in dental medicine · 2023Review
- Effects of Plant Extracts on Dentin Bonding Strength: A Systematic Review and Meta-Analysis.Frontiers in bioengineering and biotechnology · 2022Review
- A novel dentin bonding scheme based on extrafibrillar demineralization combined with covalent adhesion using a dry-bonding technique.Bioactive materials · 2021Article
- Inhibition of matrix metalloproteinases: a troubleshooting for dentin adhesion.Restorative dentistry & endodontics · 2020Review
- Advanced characterization of surface-modified nanoparticles and nanofilled antibacterial dental adhesive resins.Scientific reports · 2020Article
- Effects of calcium-phosphate, laser and adhesive on dentin permeability and bond strength.Heliyon · 2020Article
- Multifunctional monomer acts as co-initiator and crosslinker to provide autonomous strengthening with enhanced hydrolytic stability in dental adhesives.Dental materials : official publication of the Academy of Dental Materials · 2020Article
- Threats to adhesive/dentin interfacial integrity and next generation bio-enabled multifunctional adhesives.Journal of biomedical materials research. Part B, Applied biomaterials · 2019Review
- High-performance therapeutic quercetin-doped adhesive for adhesive-dentin interfaces.Scientific reports · 2017Article
- Epigallocatechin-3-gallate and Epigallocatechin-3-O-(3-O-methyl)-gallate Enhance the Bonding Stability of an Etch-and-Rinse Adhesive to Dentin.Materials (Basel, Switzerland) · 2017Article
- Advancing Discontinuous Fiber-Reinforced Composites above Critical Length for Replacing Current Dental Composites and Amalgam.Journal of nature and science · 2017Article
- Clinical evaluation of ceramic inlays and onlays fabricated with two systems: 12-year follow-up.Clinical oral investigations · 2016Article
- Cross-linked dry bonding: A new etch-and-rinse technique.Dental materials : official publication of the Academy of Dental Materials · 2016Article
- Mimicking nature: Self-strengthening properties in a dental adhesive.Acta biomaterialia · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
Abstract
objectivesThe lack of durability in resin-dentine bonds led to the use of chlorhexidine as MMP-inhibitor to prevent the degradation of hybrid layers. Biomimetic remineralisation is a concept-proven approach in preventing the degradation of resin-dentine bonds. The purpose of this study is to examine the integrity of aged resin-dentine interfaces created with a nanofiller-containing etch-and-rinse adhesive after the application of these two approaches.
methodsThe more established MMP-inhibition approach was examined using a parallel in vivo and in vitro ageing design to facilitate comparison with the biomimetic remineralisation approach using an in vitro ageing design. Specimens bonded without chlorhexidine exhibited extensive degradation of the hybrid layer after 12 months of in vivo ageing.
resultsDissolution of nanofillers could be seen within a water-rich zone within the adhesive layer. Although specimens bonded with chlorhexidine exhibited intact hybrid layers, water-rich regions remained in those hybrid layers and degradation of nanofillers occurred within the adhesive layer. Specimens subjected to in vitro biomimetic remineralisation followed by in vitro ageing demonstrated intrafibrillar collagen remineralisation within hybrid layers and deposition of mineral nanocrystals in nanovoids within the adhesive.
conclusionsThe impact was realized by understanding the lack of an inherent mechanism to remove water from resin-dentine interfaces as the critical barrier to progress in bonding with the etch-and-rinse technique. The experimental biomimetic remineralisation strategy offers a creative solution for incorporating a progressive hydration mechanism to achieve this goal, which warrants its translation into a clinically applicable technique.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.