Evidence map›Paper›PMID 21215329›Full record

ArticleNanomedicine : nanotechnology, biology, and medicine2011

Multimodal imaging of dendritic cells using a novel hybrid magneto-optical nanoprobe.

Patrick S Mackay, Gert-Jan Kremers, Saho Kobukai, Jared G Cobb, Alex Kuley, Sandra J Rosenthal, Dmitry S Koktysh, John C Gore, Wellington Pham

Abstract read
In one paragraph

Article in Nanomedicine : nanotechnology, biology, and medicine, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. Review
  8. Article
  9. Review
  10. Cell delivery of therapeutic nanoparticles.Progress in molecular biology and translational science · 2011
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Patrick S MackayInstitute of Imaging Science, Vanderbilt University, Nashville, Tennessee, USA.
Gert-Jan Kremers
Saho Kobukai
Jared G Cobb
Alex Kuley
Sandra J Rosenthal
Dmitry S Koktysh
John C Gore
Wellington Pham

Funding

TARGETING NOTCH 3 IN LUNG CANCERP50CA090949 · NCI · VANDERBILT UNIVERSITY · PI DATTA, PRAN K · 2001 to 2011
$24.1M
Vanderbilt In Vivo Cellular and Molecular Imaging CenterP50CA128323 · NCI · VANDERBILT UNIVERSITY · PI SHYR, YU · 2008 to 2012
$6.8M
Neuro - Molecular Imaging of Delivery Across BBBK01AG026366 · NIA · VANDERBILT UNIVERSITY · PI PHAM, WELLINGTON · 2006 to 2010
$602k
Develop hybrid optical-magneto nanoprobes for tracking dendritic cellsR03EB009524 · NIBIB · VANDERBILT UNIVERSITY · PI KOKTYSH, DMITRY S, PHAM, WELLINGTON · 2009 to 2010
$155k
NCI NIH HHS 5P50CA090949NCI NIH HHS P50 CA090949NCI NIH HHS P50 CA128323NCI NIH HHS P50CA128323-01A1NIA NIH HHS K01 AG026366NIA NIH HHS K01AG026366NIBIB NIH HHS 1R03EB009524NIBIB NIH HHS R03 EB009524
6 · The paper itself

Abstract

A transfecting agent-coated hybrid imaging nanoprobe (HINP) composed of visible and near-infrared (NIR) light emitting quantum dots (QDs) tethered to superparamagnetic iron oxide (SPIO) nanoparticles was developed. The surface modification of QDs and SPIO particles and incorporation of dual QDs within the SPIO were characterized by dynamic light scattering (DLS), quartz crystal microbalance (QCM) analysis and atomic force microscopy (AFM). The optical contrasting properties of HINP were characterized by absorption and photoluminescence spectroscopy and fluorescence imaging. Multicolor HINP was used in imaging the migration of dendritic cells (DCs) by optical, two-photon and magnetic resonance imaging techniques. FROM THE CLINICAL EDITOR: The development of a transfecting agent-coated hybrid imaging nanoprobe (HINP) composed of visible and near-infrared light emitting quantum dots (QDs) tethered to superparamagnetic iron oxide nanoparticles is reported in this paper. Multicolor HINP was used in imaging the migration of dendritic cells by optical, two-photon and magnetic resonance imaging techniques.

Indexed as

AnimalsCells, CulturedDendritic CellsDiagnostic ImagingMagnetite NanoparticlesMiceMice, Inbred C57BLMicroscopy, Atomic ForceNanotechnologyQuantum DotsMagnetite Nanoparticles

Identifiers

PMID21215329
PMCPMC3148276

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.