Evidence map›Paper›PMID 21215251›Full record

ReviewArchives of biochemistry and biophysics2011

The grape antioxidant resveratrol for skin disorders: promise, prospects, and challenges.

Mary Ndiaye, Carol Philippe, Hasan Mukhtar, Nihal Ahmad

Abstract readReview
In one paragraph

Review in Archives of biochemistry and biophysics, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 60 papers.

0numbers the graph read from it
0cells of the map it votes in
60citing papers in PubMed
12.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

60 citing papers in PubMed, 201 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Chemopreventive Effects of Resveratrol and Curcumin on Melanoma Growth in C57BL/6 Mice.Asian Pacific journal of cancer prevention : APJCP · 2025
    Article
  5. Review
  6. Review
  7. Review
  8. Article
  9. Review
  10. Bioactive Compounds for Combating Oxidative Stress in Dermatology.International journal of molecular sciences · 2023
    Review
  11. The effect of Dermalix® on colon anastomosis leakage: experimental study.Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES · 2023
    Article
  12. Article
  13. Article
  14. Singlet Oxygen Quenching by Resveratrol Derivatives.Photochemistry and photobiology · 2023
    Article
  15. Article
  16. Article
  17. Article
  18. Aqueous Chlorination of D-Limonene.Molecules (Basel, Switzerland) · 2022
    Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Mary NdiayeDepartment of Dermatology, University of Wisconsin, Madison, WI 53706, USA.
Carol Philippe
Hasan Mukhtar
Nihal Ahmad
University of Wisconsin–Madison · USUniversity of Wisconsin Carbone Cancer Center · US

Funding

Role of Polo-Like Kinase-1 in Melanocytic TransformationR01AR059130 · NIAMS · UNIVERSITY OF WISCONSIN-MADISON · PI AHMAD, NIHAL · 2010 to 2019
$3.8M
SELECT Pre-Clinical Trial of Prostate CancerR01CA114060 · NCI · UNIVERSITY OF WISCONSIN-MADISON · PI AHMAD, NIHAL · 2006 to 2010
$1.3M
Enhancing Bioavailability of ResveratrolR21CA149560 · NCI · UNIVERSITY OF WISCONSIN-MADISON · PI AHMAD, NIHAL, BAILEY, HOWARD H. · 2010 to 2011
$496k
NCI NIH HHS 1R21CA149560NCI NIH HHS R01 CA114060NCI NIH HHS R01CA114060NCI NIH HHS R21 CA149560NIAMS NIH HHS 1R01AR059130NIAMS NIH HHS R01 AR059130
6 · The paper itself

Abstract

Resveratrol, a phytoalexin antioxidant found in red grapes, has been shown to have both chemopreventive and therapeutic effects against many diseases and disorders, including those of the skin. Studies have shown protective effects of resveratrol against ultraviolet radiation-mediated oxidative stress and cutaneous damages including skin cancer. Because many of the skin conditions stem from ultraviolet radiation and oxidative stress, this antioxidant appears to have promise and prospects against a wide range of cutaneous disorders including skin aging and skin cancers. However, there are a few roadblocks in the way of this promising agent regarding its translation from the bench to the bedside. This review discusses the promise and prospects of resveratrol in the management of skin disorders and the associated challenges.

Indexed as

AnimalsAntioxidantsHumansOxidative StressResveratrolSkinSkin DiseasesStilbenesVitisAntioxidantsResveratrolStilbenes

Identifiers

PMID21215251
PMCPMC3060966
OpenAlexW2032019525

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.