ReviewEpilepsia2011
Epilepsy as a spectrum disorder: Implications from novel clinical and basic neuroscience.
Review in Epilepsia, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
54 citing papers in PubMed, 2 syntheses or guidelines pooled it, 139 citations in OpenAlex.
- Relationship of epilepsy on the linguistic-cognitive profile of children with ASD: A systematic review of the literature.Frontiers in psychology · 2023Pooled it
- The P300 Event-Related Potential Component and Cognitive Impairment in Epilepsy: A Systematic Review and Meta-analysis.Frontiers in neurology · 2019Pooled it
- Age dependent seizure susceptibility of CA2 hippocampal neurons.Frontiers in cellular neuroscience · 2025Review
- The eACT study design and methods: A sequential, multiple assignment, randomized trial of A novel adherence intervention for youth with epilepsy.Contemporary clinical trials · 2024Article
- Reversible synaptic adaptations in a subpopulation of murine hippocampal neurons following early-life seizures.The Journal of clinical investigation · 2024Article
- Health Disparities in Pediatric Epilepsy: Methods and Lessons Learned.Journal of clinical psychology in medical settings · 2023Review
- Effects of altered excitation-inhibition imbalance by repetitive transcranial magnetic stimulation for self-limited epilepsy with centrotemporal spikes.Frontiers in neurology · 2023Article
- A Literature Review of Similarities Between and Among Patients With Autism Spectrum Disorder and Epilepsy.Cureus · 2023Review
- Access to Care for US Children with Co-Occurrence of Autism Spectrum Disorder and Epilepsy.Children (Basel, Switzerland) · 2022Article
- Interictal epileptiform discharges changed epilepsy-related brain network architecture in BECTS.Brain imaging and behavior · 2022Article
- Ameliorating Effect of Umbilical Cord Mesenchymal Stem Cells in a Human Induced Pluripotent Stem Cell Model of Dravet Syndrome.Molecular neurobiology · 2022Article
- Shared Etiology in Autism Spectrum Disorder and Epilepsy with Functional Disability.Behavioural neurology · 2022Review
- Changes in Pre- and Postsurgery for Drug Resistant Epilepsy: Cognition and Sleep.BioMed research international · 2022Article
- The psychosocial impact of COVID-19 within the first six months of the pandemic on youth with epilepsy and their caregivers.Epilepsy & behavior : E&B · 2021Article
- Over 10-Year Outcomes of Infantile-Onset Epilepsies.Journal of clinical medicine · 2021Article
- Multipronged Attack of Stem Cell Therapy in Treating the Neurological and Neuropsychiatric Symptoms of Epilepsy.Frontiers in pharmacology · 2021Review
- Alzheimer-like amyloid and tau alterations associated with cognitive deficit in temporal lobe epilepsy.Brain : a journal of neurology · 2020Article
- Brain-Derived Neurotrophic Factor in Brain Disorders: Focus on Neuroinflammation.Molecular neurobiology · 2019Review
- Early Seizures Prematurely Unsilence Auditory Synapses to Disrupt Thalamocortical Critical Period Plasticity.Cell reports · 2018Article
- Benign and severe early-life seizures: a round in the first year of life.Italian journal of pediatrics · 2018Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
Abstract
Epilepsy is increasingly recognized as a disease that reaches well beyond seizures. Cognitive and psychiatric impairment affect half of all epilepsy patients, and to date there are no specific treatments for these symptoms. It is unclear which of these comorbidities are directly due to seizures and which are due to separable mechanisms that are parallel to those underlying ictal activity. Cellular and molecular mechanisms underlying synaptic modulation are central to both the ictal and nonictal changes in epilepsy. Current diagnostic methods are rapidly advancing to better delineate the nature and extent of ictal activity, and could soon be critical in identifying patterns unique to the cognitive and psychiatric comorbidities.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.