ArticleFrontiers in neurology2010
Spread deficits in initiation, speed and accuracy of horizontal and vertical automatic saccades in dementia with lewy bodies.
Article in Frontiers in neurology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed, 27 citations in OpenAlex.
- Eye tracking as a digital biomarker in neurodegenerative diseases.Journal of neurology · 2026Review
- Progressive Supranuclear Palsy (PSP): An Orthoptic Assessment.The British and Irish orthoptic journal · 2026Review
- Eye movement abnormalities in Alzheimer's disease and other neurodegenerative dementias: insights from current evidence and priorities for future research.Frontiers in ophthalmology · 2025Review
- Tests of abnormal gaze behavior increase the accuracy of mild cognitive impairment assessments.Scientific reports · 2024Article
- Detecting Abnormal Eye Movements in Patients with Neurodegenerative Diseases - Current Insights.Eye and brain · 2024Review
- Application and progress of advanced eye movement examinations in cognitive impairment.Frontiers in aging neuroscience · 2024Review
- Eye movement changes as an indicator of mild cognitive impairment.Frontiers in neuroscience · 2023Article
- Prosaccade and Antisaccade Behavior in Fragile X-Associated Tremor/Ataxia Syndrome Progression.Movement disorders clinical practice · 2022Article
- The Disengagement of Visual Attention: An Eye-Tracking Study of Cognitive Impairment, Ethnicity and Age.Brain sciences · 2020Article
- Slow saccades in cerebellar disease.Cerebellum & ataxias · 2019Review
- Vergence and Strabismus in Neurodegenerative Disorders.Frontiers in neurology · 2018Review
- Basic and translational neuro-ophthalmology of visually guided saccades: disorders of velocity.Expert review of ophthalmology · 2017Article
- Objective Evaluation of Vergence Disorders and a Research-Based Novel Method for Vergence Rehabilitation.Translational vision science & technology · 2016Article
- Abnormalities of fixation, saccade and pursuit in posterior cortical atrophy.Brain : a journal of neurology · 2015Article
- Specific saccade deficits in patients with Alzheimer's disease at mild to moderate stage and in patients with amnestic mild cognitive impairment.Age (Dordrecht, Netherlands) · 2013Article
- Eye movements in patients with neurodegenerative disorders.Nature reviews. Neurology · 2013Review
- Long latency and high variability in accuracy-speed of prosaccades in Alzheimer's disease at mild to moderate stage.Dementia and geriatric cognitive disorders extra · 2011Article
- Different effects of double-pulse TMS of the posterior parietal cortex on reflexive and voluntary saccades.Frontiers in human neuroscience · 2011Article
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Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundMosimann et al. (2005) reported prolongation of saccade latency of prosaccades in dementia with Lewy body (DLB). The goal of this study is to go further examining all parameters, such as rates of express latency, but also accuracy and velocity of saccades, and their variability.
methodsWe examined horizontal and vertical saccades in 10 healthy elderly subjects and 10 patients with DLB. Two tasks were used: the gap (fixation target extinguishes prior to target onset) and the overlap (fixation stays on after target onset). Eye movements were recorded with the Eyelink II eye tracker.
resultsThe main findings were: (1) as for healthy, latencies were shorter in the gap than in the overlap task (a gap effect); (2) for both tasks latency of saccades was longer for DLB patients and for all directions; (3) express latency in the gap task was absent for large majority of DLB patients while such saccades occurred frequency for controls; (4) accuracy and peak velocity were lower in DLB patients; (5) variability of all parameters was abnormally high in DLB patients.
conclusionsAbnormalities of all parameters, latency, accuracy and peak velocity reflect spread deficits in cortical-subcortical circuits involved in the triggering and execution of saccades.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.