Evidence map›Paper›PMID 21212024›Full record

ArticleTravel medicine and infectious disease2011

Manifestations of paediatric Leishmania infantum infections in Malta.

David Pace, Thomas N Williams, Alicja Grochowska, Alexandra Betts, Simon Attard-Montalto, Michael J Boffa, Cecil Vella

Open access · hybridAbstract read
In one paragraph

Article in Travel medicine and infectious disease, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 19 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Review
  5. A Rare Case of Imported Cutaneous Leishmaniasis Caused byTropical medicine and infectious disease · 2023
    Article
  6. Article
  7. Article
  8. [Skin biopsy of inflammatory skin diseases in childhood-when is it reasonable?]Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete · 2018
    Review
  9. Article
  10. From the dermatologikum hamburg: quiz.Dermatology practical & conceptual · 2013
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

David PacePaediatric Infectious Diseases Clinic, Mater Dei Hospital, Msida, Malta. dpace@go.net.mt
Thomas N Williams
Alicja Grochowska
Alexandra Betts
Simon Attard-Montalto
Michael J Boffa
Cecil Vella
Mater Dei Hospital · MTKenya Medical Research Institute · KESir Paul Boffa Hospital · MT

Funding

Wellcome Trust 076934Wellcome Trust 091758
6 · The paper itself

Abstract

Leishmania infantum is endemic in the Maltese archipelago, a group of islands in the Mediterranean which are visited frequently by tourists from Northern European countries. The burden of leishmaniasis is highest in children who may present with cutaneous or visceral manifestations. We describe systematically the manifestations, diagnosis and management of leishmaniasis in children <14 years of age, who had a histopathological diagnosis of leishmaniasis in Malta, from 2004 to 2008. Eleven children were diagnosed with leishmaniasis; 8 children (15-44 months of age) had visceral disease and three (aged 9-13 years) suffered cutaneous infections. Prolonged high grade fever, pallor, hepatosplenomegaly, and pancytopenia were common presenting features of visceralisation. Diagnosis was based on the visualisation of amastigotes from bone marrow aspirates. Pentavalent antimonials were associated with treatment failure in two children, whilst liposomal amphotericin B was curative in all. Children with cutaneous leishmaniasis had dry crusted ulcero-nodular lesions on exposed areas which responded to intra-lesional instillation of sodium stibogluconate or to cryotherapy. Leishmaniasis should be included in the differential diagnosis of fever and hepatosplenomegaly or chronic cutaneous lesions in children who travel to Malta.

Indexed as

AdolescentAnimalsAntiprotozoal AgentsChildChild, PreschoolFemaleHumansInfantLeishmania infantumLeishmaniasis, VisceralMaleMaltaPhlebotomusAntiprotozoal Agents

Identifiers

PMID21212024
PMCPMC3115057
OpenAlexW1972261460

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.