Evidence map›Paper›PMID 21211026›Full record

ArticleItalian journal of pediatrics2011

Antimicrobial resistance among Escherichia coli that cause childhood community-acquired urinary tract infections in Northern Italy.

Alessandra Caracciolo, Alberto Bettinelli, Claudio Bonato, Clementina Isimbaldi, Alessandro Tagliabue, Laura Longoni, Mario G Bianchetti

Open access · goldAbstract readComparative Study
In one paragraph

Article in Italian journal of pediatrics, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
2.4field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 36 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Alterations in chromosomal genesMicrobial genomics · 2021
    Article
  6. Three-Year Trend inChildren (Basel, Switzerland) · 2021
    Article
  7. Article
  8. Review
  9. Article
  10. Antibiotic Resistance in Pediatric Urinary Tract Infections.Current infectious disease reports · 2016
    Review
  11. Article
  12. Article
  13. Review
  14. Increase resistant rates and ESBL production between E. coli isolates causing urinary tract infection in young patients from Iran.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2012
    Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Alessandra CaraccioloDepartment of Clinical Laboratory, San Leopoldo Mandic Hospital, Merate-Lecco, Italy.
Alberto Bettinelli
Claudio Bonato
Clementina Isimbaldi
Alessandro Tagliabue
Laura Longoni
Mario G Bianchetti
Ospedale Regionale di Mendrisio · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundResistance rate of Escherichia coli against antimicrobials that are commonly prescribed in pediatric urinary tract infections is currently a matter of concern.

methodsThe antimicrobial susceptibility patterns of uropathogenic Escherichia coli strains to the common antibimcrobials ampicillin, cotrimoxazole, coamoxyclav, ceftazidime, ceftriaxone, nitrofurantoin, and gentamycin were determined in 177 children aged from 2 to 36 months. They presented with their first symptomatic community acquired urinary tract infection at the Department of Pediatrics, San Leopoldo Mandic Hospital, Merate-Lecco.

resultsHigh rates of ampicillin (inpatients: 50%; outpatients: 52%) resistance were identified. The resistance for cotrimoxazole (inpatients: 22%; outpatients: 15%) and especially coamoxyclav (inpatients: 6%; outpatients: 10%) was less pronounced than that to ampicillin. No resistance or less than 1% of resistance was identified for ceftazidime, ceftriaxone, nitrofurantoin, and gentamycin both in inpatients and in outpatients.

conclusionsItalian children affected with a community acquired urinary tract infection are initially managed orally with coamoxyclav or parenterally with ceftriaxone. The results of the present retrospective analysis support this attitude. Parenteral ceftriaxone or an aminoglycoside should be considered for patients on antimicrobial prophylaxis or recently prescribed antimicrobials.

Indexed as

Drug Resistance, BacterialAnti-Bacterial AgentsChild, PreschoolCross InfectionEscherichia coliEscherichia coli InfectionsFemaleHumansInfantItalyMaleRetrospective StudiesUrinary Tract InfectionsAnti-Bacterial Agents

Identifiers

PMID21211026
PMCPMC3023741
OpenAlexW2112646751

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.