Evidence map›Paper›PMID 21210894›Full record

ArticleNeurogastroenterology and motility2011

Performance characteristics of the measurement of gastric volume using single photon emission computed tomography.

M Breen, M Camilleri, D Burton, A R Zinsmeister

Open access · greenAbstract readComparative Study
In one paragraph

Article in Neurogastroenterology and motility, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 1 pooled it
2.6field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 1 synthesis or guideline pooled it, 56 citations in OpenAlex.

  1. Changes in Time of Gastric Emptying After Surgical and Endoscopic Bariatrics and Weight Loss: A Systematic Review and Meta-Analysis.Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association · 2020
    Pooled it
  2. A Randomized, Controlled Trial of Efficacy and Safety of Cannabidiol in Idiopathic and Diabetic Gastroparesis.Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association · 2023
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  13. Postprandial symptoms in patients with symptoms of gastroparesis: roles of gastric emptying and accommodation.American journal of physiology. Gastrointestinal and liver physiology · 2022
    Article
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  16. Associations of gastric volumes, ingestive behavior, calorie and volume intake, and fullness in obesity.American journal of physiology. Gastrointestinal and liver physiology · 2020
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  18. Review
  19. Relationship of gastric emptying or accommodation with satiation, satiety, and postprandial symptoms in health.American journal of physiology. Gastrointestinal and liver physiology · 2017
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  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

M BreenClinical Enteric Neuroscience Translational and Epidemiological Research (CENTER), Mayo Clinic, Rochester, MN 55905, USA.
M Camilleri
D Burton
A R Zinsmeister
Mayo Clinic in Florida · USMayo Clinic · US

Funding

Pharmacogenomics of Gastric Function &Weight in ObesityR01DK067071 · NIDDK · MAYO CLINIC ROCHESTER · PI CAMILLERI, MICHAEL L. · 2004 to 2020
$4.7M
Irritable bowel syndrome-diarrhea: the role of gluten intolerance and HLA-DQ2RC1DK086182 · NIDDK · MAYO CLINIC ROCHESTER · PI CAMILLERI, MICHAEL L. · 2009 to 2010
$1.0M
Cannabinoid Mechanisms in Human Gastrointestinal Motor and Sensory FunctionsR01DK079866 · NIDDK · MAYO CLINIC ROCHESTER · PI CAMILLERI, MICHAEL L. · 2009 to 2010
$752k
NIDDK NIH HHS 1RC1-DK086182NIDDK NIH HHS R01 DK067071NIDDK NIH HHS R01 DK079866NIDDK NIH HHS R01-DK079866NIDDK NIH HHS R01-DK67071NIDDK NIH HHS RC1 DK086182
6 · The paper itself

Abstract

backgroundA non-invasive single photon emission computed tomography (SPECT) method was developed and validated to measure gastric volumes (GV). The natural variation in gastric volume responses and performance characteristics of SPECT imaging are unclear.

methodsThe primary aim of this study was to assess the performance characteristics of SPECT imaging by estimating the inter-individual coefficients of variation (COV) in fasting and postprandial GV in 433 participants in prior research studies over the last decade, and the intra-individual COV in all volunteers who had undergone at least two studies. The secondary aim was to assess the relationship of gender, BMI and age on GV. KEY

resultsThe COV(INTER) for all subjects in the study (n = 433) was 32.6% fasting, 16.0% fed, and 19.0%Δ fed - fasting. The COV(INTRA) for 47 subjects with repeat estimates of gastric volume was 37.0% fasting, 17.6% fed, and 22.0%Δ fed - fasting. COV(INTRA) was stable over time interval from 2 to 60 months. There were no significant differences by gender or subgroups. Mean fed and gastric accommodation volumes were associated with age and BMI but the magnitude of variation attributable was <5%. CONCLUSIONS & INFERENCES: COV(INTRA) and COV(INTER) of GV by SPECT are very similar, and there is a small effect of age and BMI. These data are important for planning future studies of GV and further validate SPECT for studies of gastric motility disorders and obesity.

Indexed as

AdultAge FactorsBody Mass IndexFastingFemaleGastrointestinal MotilityHumansMaleMiddle AgedOrgan SizePostprandial PeriodSex FactorsStomachTomography, Emission-Computed, Single-Photon

Identifiers

PMID21210894
PMCPMC3105214
OpenAlexW1486750854

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.