ArticleJournal of agricultural and food chemistry2011
Multiple receptors as targets of Cry toxins in mosquitoes.
Article in Journal of agricultural and food chemistry, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
30 citing papers in PubMed, 93 citations in OpenAlex.
- Aedes aegypti strain selected with Bacillus thuringiensis svar. israelensis larvicide for 50 generations remains susceptible and exhibited increased fitness.Parasites & vectors · 2025Article
- Carry-over effects of Bacillus thuringiensis on tolerant Aedes albopictus mosquitoes.Parasites & vectors · 2024Article
- Evaluation of a long-lasting microbial larvicide against Culex quinquefasciatus and Aedes aegypti under laboratory and a semi-field trial.Parasites & vectors · 2024Article
- CRISPR-Cas9 knockout of membrane-bound alkaline phosphatase or cadherin does not confer resistance to Cry toxins in Aedes aegypti.PLoS neglected tropical diseases · 2024Article
- Performance insights into spray-dryer microencapsulated Bacillus thuringiensis cry pesticidal proteins with gum arabic and maltodextrin for effective pest control.Applied microbiology and biotechnology · 2024Article
- Article
- The role of glycoconjugates as receptors for insecticidal proteins.FEMS microbiology reviews · 2023Review
- De novo determination of mosquitocidal Cry11Aa and Cry11Ba structures from naturally-occurring nanocrystals.Nature communications · 2022Article
- Role of Lectin in the Response ofFrontiers in immunology · 2022Review
- Aedes aegypti continuously exposed to Bacillus thuringiensis svar. israelensis does not exhibit changes in life traits but displays increased susceptibility for Zika virus.Parasites & vectors · 2021Article
- Review
- Streamlined phage display library protocols for identification of insect gut binding peptides highlight peptide specificity.Current research in insect science · 2021Article
- Aedes cadherin receptor that mediates Bacillus thuringiensis Cry11A toxicity is essential for mosquito development.PLoS neglected tropical diseases · 2020Article
- Long-term exposure of Aedes aegypti to Bacillus thuringiensis svar. israelensis did not involve altered susceptibility to this microbial larvicide or to other control agents.Parasites & vectors · 2018Article
- Article
- An Intramolecular Salt Bridge in Bacillus thuringiensis Cry4Ba Toxin Is Involved in the Stability of Helix α-3, Which Is Needed for Oligomerization and Insecticidal Activity.Applied and environmental microbiology · 2017Article
- Transcriptional cellular responses in midgut tissue of Aedes aegypti larvae following intoxication with Cry11Aa toxin from Bacillus thuringiensis.BMC genomics · 2015Article
- Article
- Review
- Alkaline phosphatases and aminopeptidases are altered in a Cry11Aa resistant strain of Aedes aegypti.Insect biochemistry and molecular biology · 2014Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
Abstract
Bacillus thuringiensis (Bt) produces inclusions that are composed of proteins known as crystal proteins or Cry toxins. Due to their high specificity and their safety to humans and the environment, these Cry toxins are considered to be valuable alternatives to chemical pesticides in insect control programs. It is believed that Cry toxin-induced membrane pore formation is responsible for insect toxicity. The molecular mechanism of pore formation involves recognition and subsequent binding of the toxin to membrane receptors. This binding is accompanied by toxin oligomerization and transfer of domain I helices of the toxin to the lipid-water interface. This toxin insertion creates pores that lyse the cells. Several receptors from lepidopteran, coleopteran, and dipteran insects have been well characterized. This paper provides an overview of the understanding of the interactions between Cry toxin and multiple receptors in mosquitoes, in particular Aedes aegypti and reviews the manner by which the receptors were identified and characterized, with a focus on three proteins, cadherin, alkaline phosphatase, and aminopeptidase-N.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.