ArticleEuropean journal of applied physiology2011
Strong ion reserve: a viewpoint on acid base equilibria and buffering.
Article in European journal of applied physiology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
3 citing papers in PubMed.
- Article
- Quantifying pH-induced changes in plasma strong ion difference during experimental acidosis: clinical implications for base excess interpretation.Journal of applied physiology (Bethesda, Md. : 1985) · 2024Article
- Role of Crystalloids in the Perioperative Setting: From Basics to Clinical Applications and Enhanced Recovery Protocols.Journal of clinical medicine · 2023Review
Corrections and comments
- Erratum issued
Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Evidence suggests that strong ions can exist reversibly bound to proteins in a pH-dependent manner and that they can be recruited into the biological solution, modulating its strong ion difference in a process that opposes the acid base disturbances imposed on the system. These recruitable strong ions represent the solution's 'strong ion reserve'. The physiologic [corrected] role of these protein-bound strong ions [corrected] in the buffering of acid base disorders is discussed.
Indexed as
Identifiers
21210280What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.