Evidence map›Paper›PMID 21210127›Full record

ArticleChild's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery2011

Children with tethered cord syndrome of different etiology benefit from microsurgery-a single institution experience.

Pantelis Stavrinou, Mathias Kunz, Markus Lehner, Alfred Heger, Wolfgang Müller-Felber, Joerg-Christian Tonn, Aurelia Peraud

Abstract read
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In one paragraph

Article in Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.

  1. Disparities in indications and outcomes reporting for pediatric tethered cord surgery: The need for a standardized outcome assessment tool.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2024
    Pooled it
  2. Tethered cord prevalence among patients with prenatal or postnatal myelomeningocele repair.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2024
    Article
  3. Article
  4. Early de-tethering: analysis of urological and clinical consequences in a series of 40 children.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2021
    Article
  5. Article
  6. Long-term evaluation of intraoperative neurophysiological monitoring-assisted tethered cord surgery.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2017
    Observational
  7. Article
  8. Article
  9. Intraoperative neurophysiology in tethered cord surgery: techniques and results.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2013
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Pantelis StavrinouDepartment of Neurosurgery, Klinikum Grosshadern, Ludwig-Maximilians-University of Munich, Munich, Germany.
Mathias Kunz
Markus Lehner
Alfred Heger
Wolfgang Müller-Felber
Joerg-Christian Tonn
Aurelia Peraud
Ludwig-Maximilians-Universität München · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe term "tethered cord syndrome" (TCS) illustrates, according to the literature, both a separate diagnosis, as well as a combination of symptoms in the context of dysraphic conditions. The common denominator is the increased tension and abnormal stretching of the spinal cord, caused by tissue attachments that limit its movement in the spinal canal. In light of the fact that no real data exists regarding the management of these patients, the purpose of this single institutional study is to underscore management strategies and discuss the results, pitfalls, and the treatment of pediatric patients with tethered cord syndrome. METHODS AND

resultsThe clinical outcome in 20 pediatric patients was studied retrospectively. Ten children with closed spinal dysraphism, nine with tethering after postpartum myelomeningocele repair, and one child with an infected open dermal sinus were included. A total of 22 detethering procedures were performed. The most common symptoms prior to surgery were muscle weakness and urinary dysfunction, followed by foot deformities and pain. Of all symptoms, pain responded most favorably to surgical treatment. There was improvement in 11 out of 15 patients with preoperative motor deficits, while that was the case in 11 out of 16 patients with urinary dysfunction.

conclusionsIn view of the lack of evidence regarding the treatment of children with tethered cord syndrome, the best way to aim for a favorable outcome is correct indication for surgical intervention, combined with the implementation of technical advancements, such as intraoperative neurophysiological monitoring and ultrasound.

Indexed as

MicrosurgeryAdolescentChildChild, PreschoolFemaleHumansInfantMaleNeural Tube DefectsNeurosurgical ProceduresRecovery of FunctionRetrospective StudiesTreatment Outcome

Identifiers

PMID21210127
OpenAlexW1978248228

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.