Evidence map›Paper›PMID 21209893›Full record

ArticlePloS one2010

Rising population cost for treating people living with HIV in the UK, 1997-2013.

Sundhiya Mandalia, Roshni Mandalia, Gary Lo, Tim Chadborn, Peter Sharott, Mike Youle, Jane Anderson, Guy Baily, Ray Brettle, Martin Fisher and 12 more

Abstract read
In one paragraph

Article in PloS one, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Cost of noninfectious comorbidities in patients with HIV.ClinicoEconomics and outcomes research : CEOR · 2013
    Review
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors.

Sundhiya MandaliaNPMS-HHC Coordinating and Analytic Centre, London, United Kingdom.
Roshni Mandalia
Gary Lo
Tim Chadborn
Peter Sharott
Mike Youle
Jane Anderson
Guy Baily
Ray Brettle
Martin Fisher
Mark Gompels
George Kinghorn
Margaret Johnson
Brendan McCarron
Anton Pozniak
Alan Tang
John Walsh
David White
Ian Williams
Brian Gazzard
Eduard J Beck
NPMS-HHC Steering Group

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe number of people living with HIV (PLHIV) is increasing in the UK. This study estimated the annual population cost of providing HIV services in the UK, 1997-2006 and projected them 2007-2013.

methodsAnnual cost of HIV treatment for PLHIV by stage of HIV infection and type of ART was calculated (UK pounds, 2006 prices). Population costs were derived by multiplying the number of PLHIV by their annual cost for 1997-2006 and projected 2007-2013.

resultsAverage annual treatment costs across all stages of HIV infection ranged from £17,034 in 1997 to £18,087 in 2006 for PLHIV on mono-therapy and from £27,649 in 1997 to £32,322 in 2006 for those on quadruple-or-more ART. The number of PLHIV using NHS services rose from 16,075 to 52,083 in 2006 and was projected to increase to 78,370 by 2013. Annual population cost rose from £104 million in 1997 to £483 million in 2006, with a projected annual cost between £721 and £758 million by 2013. When including community care costs, costs increased from £164 million in 1997, to £683 million in 2006 and between £1,019 and £1,065 million in 2013.

conclusionsIncreased number of PLHIV using NHS services resulted in rising UK population costs. Population costs are expected to continue to increase, partly due to PLHIV's longer survival on ART and the relative lack of success of HIV preventing programs. Where possible, the cost of HIV treatment and care needs to be reduced without reducing the quality of services, and prevention programs need to become more effective. While high income countries are struggling to meet these increasing costs, middle- and lower-income countries with larger epidemics are likely to find it even more difficult to meet these increasing demands, given that they have fewer resources.

Indexed as

AlgorithmsAnti-HIV AgentsAntiretroviral Therapy, Highly ActiveCosts and Cost AnalysisEconomics, MedicalFemaleHealth Care CostsHIV InfectionsHumansMaleModels, StatisticalProspective StudiesRegression AnalysisUnited KingdomAnti-HIV Agents

Identifiers

PMID21209893
PMCPMC3012705

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.