Evidence map›Paper›PMID 21209718›Full record

ArticleJournal of nutrition and metabolism2010

Vitamin d status is not associated with outcomes of experimentally-induced muscle weakness and pain in young, healthy volunteers.

Susan M Ring, Erin A Dannecker, Catherine A Peterson

Open access · goldAbstract read
In one paragraph

Article in Journal of nutrition and metabolism, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.

  1. Pooled it
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  3. Article
  4. Review
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  7. Article
  8. Modern rehabilitation in osteoporosis, falls, and fractures.Clinical medicine insights. Arthritis and musculoskeletal disorders · 2014
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Susan M RingDepartment of Nutrition and Exercise Physiology, 217 Gwynn Hall, University of Missouri-Columbia, Columbia, MO 65211, USA.
Erin A Dannecker
Catherine A Peterson
University of Missouri · US

Funding

Measures and Mechanisms of Muscle Pain in HumansK01AR050146 · NIAMS · UNIVERSITY OF MISSOURI-COLUMBIA · PI DANNECKER, ERIN ALICE · 2004 to 2008
$626k
NIAMS NIH HHS K01 AR050146
6 · The paper itself

Abstract

Vitamin D receptors have been identified in skeletal muscle; and symptoms of vitamin D deficiency include muscle weakness and pain. Moreover, increased serum 25-hydroxyvitamin D (25(OH)D) concentrations have been associated with improved muscle function. To further clarify the importance of vitamin D to muscle, we examined the association between vitamin D status and exercise-induced muscle pain and weakness in healthy people. Muscle damage to the elbow flexors was induced with eccentric exercise (EE) in 48 individuals (22.5 ± 3.2 yrs). Muscle pain ratings following unloaded movement and peak isometric force (IF) were collected before EE and for 4 days post-EE. Linear regression was used to determine if serum 25(OH)D was a predictor of any outcome. In males, R(2)-values from 0.48 to 1.00. R(2) for IF ranged from 0 to 0.02 and P-values from 0.48 to 1.00. In females, R(2) for pain ratings ranged from 0.01 to 0.11 and P-values from 0.14 to 0.59. R(2) for IF ranged from 0 to 0.04 and P-values from 0.41 to 0.90. In conclusion, vitamin D status did not predict muscle pain or strength after EE-induced muscle damage in young healthy men and women.

Identifiers

PMID21209718
PMCPMC3010688
OpenAlexW2116703957

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.