ArticleJournal of experimental botany2011
Rice Brittle culm 6 encodes a dominant-negative form of CesA protein that perturbs cellulose synthesis in secondary cell walls.
Article in Journal of experimental botany, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers.
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47 citing papers in PubMed, 141 citations in OpenAlex.
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- The rice BRITTLE CULM 4 gene encodes a membrane protein affecting cellulose synthesis in the secondary cell wall.Plant & cell physiology · 2025Article
- Transcriptome and co-expression network analysis reveal the genetic basis of cell wall components in maize stalks.BMC genomics · 2025Article
- Genome-wide identification of theFrontiers in plant science · 2025Article
- Characterization of Cell Wall Compositions of Sodium Azide-Induced Brittle Mutant Lines in IR64 Variety and Its Potential Application.Plants (Basel, Switzerland) · 2024Article
- Integrated VIS/NIR Spectrum and Genome-Wide Association Study for Genetic Dissection of Cellulose Crystallinity in Wheat Stems.International journal of molecular sciences · 2024Article
- An integrated QTL mapping and transcriptome sequencing provides further molecular insights and candidate genes for stem strength in rapeseed (Brassica napus L.).TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2024Article
- Reciprocal regulation of cellulose and lignin biosynthesis by the transcription factor OsTCP19.Journal of experimental botany · 2024Article
- Novel function of a putative TaCOBL ortholog associated with cold response.Molecular biology reports · 2023Article
- Genome-wide association studies for a comprehensive understanding of the genetic architecture of culm strength and yield traits in rice.Frontiers in plant science · 2023Article
- Integrating biochemical and anatomical characterizations with transcriptome analysis to dissect superior stem strength of ZS11 (Frontiers in plant science · 2023Article
- ETHYLENE RESPONSE FACTOR 34 promotes secondary cell wall thickening and strength of rice peduncles.Plant physiology · 2022Article
- Rice co-expression network analysis identifies gene modules associated with agronomic traits.Plant physiology · 2022Article
- Amino Acids Supplied through the Autophagy/Endocytosis Pathway Promote Starch Synthesis inPlants (Basel, Switzerland) · 2022Article
- Comparative Transcriptome Analysis of Softening and Ripening-Related Genes in Kiwifruit Cultivars Treated with Ethylene.Current issues in molecular biology · 2022Article
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- Identification and Fine Mapping of the Recessive GeneInternational journal of molecular sciences · 2022Article
- Characteristics and candidate genes associated with excellent stalk strength in maize (Frontiers in plant science · 2022Article
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- Rice Brittle Culm19 Encoding Cellulose Synthase Subunit CESA4 Causes Dominant Brittle Phenotype But has No Distinct Influence on Growth and Grain Yield.Rice (New York, N.Y.) · 2021Article
Corrections and comments
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The brittle culm (bc) mutants of Gramineae plants having brittle skeletal structures are valuable materials for studying secondary cell walls. In contrast to other recessive bc mutants, rice Bc6 is a semi-dominant bc mutant with easily breakable plant bodies. In this study, the Bc6 gene was cloned by positional cloning. Bc6 encodes a cellulose synthase catalytic subunit, OsCesA9, and has a missense mutation in its highly conserved region. In culms of the Bc6 mutant, the proportion of cellulose was reduced by 38%, while that of hemicellulose was increased by 34%. Introduction of the semi-dominant Bc6 mutant gene into wild-type rice significantly reduced the percentage of cellulose, causing brittle phenotypes. Transmission electron microscopy analysis revealed that Bc6 mutation reduced the cell wall thickness of sclerenchymal cells in culms. In rice expressing a reporter construct, BC6 promoter activity was detected in the culms, nodes, and flowers, and was localized primarily in xylem tissues. This expression pattern was highly similar to that of BC1, which encodes a COBRA-like protein involved in cellulose synthesis in secondary cell walls in rice. These results indicate that BC6 is a secondary cell wall-specific CesA that plays an important role in proper deposition of cellulose in the secondary cell walls.
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