ArticleDevelopment (Cambridge, England)2011
Cell migration in Drosophila optic lobe neurons is controlled by eyeless/Pax6.
Article in Development (Cambridge, England), 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
28 citing papers in PubMed, 54 citations in OpenAlex.
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- Neural specification, targeting, and circuit formation during visual system assembly.Proceedings of the National Academy of Sciences of the United States of America · 2021Article
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- Dscam1 establishes the columnar units through lineage-dependent repulsion between sister neurons in the fly brain.Nature communications · 2020Article
- Neurogenesis From Embryo to Adult - Lessons From Flies and Mice.Frontiers in cell and developmental biology · 2020Review
- N-Cadherin Orchestrates Self-Organization of Neurons within a Columnar Unit in theThe Journal of neuroscience : the official journal of the Society for Neuroscience · 2019Article
- Spatio-temporal pattern of neuronal differentiation in the Drosophila visual system: A user's guide to the dynamic morphology of the developing optic lobe.Developmental biology · 2017Article
- Revisiting the role of the Gcm transcription factor, from master regulator to Swiss army knife.Fly · 2016Article
- Cloning and Functional Analysis of Pax6 from the Hydrothermal Vent Tubeworm Ridgeia piscesae.PloS one · 2016Article
- So many pieces, one puzzle: cell type specification and visual circuitry in flies and mice.Genes & development · 2014Review
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
In the developing Drosophila optic lobe, eyeless, apterous and distal-less, three genes that encode transcription factors with important functions during development, are expressed in broad subsets of medulla neurons. Medulla cortex cells follow two patterns of cell movements to acquire their final position: first, neurons are arranged in columns below each neuroblast. Then, during pupation, they migrate laterally, intermingling with each other to reach their retinotopic position in the adult optic lobe. eyeless, which encodes a Pax6 transcription factor, is expressed early in progenitors and controls aspects of this cell migration. Its loss in medulla neurons leads to overgrowth and a failure of lateral migration during pupation. These defects in cell migration among medulla cortex cells can be rescued by removing DE-Cadherin. Thus, eyeless links neurogenesis and neuronal migration.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.