ArticleJournal of molecular neuroscience : MN2011
Fyn polymorphisms are associated with distinct personality traits in healthy Chinese-Han subjects.
Article in Journal of molecular neuroscience : MN, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
5 citing papers in PubMed, 11 citations in OpenAlex.
- Association of the Polygenic Scores for Personality Traits and Response to Selective Serotonin Reuptake Inhibitors in Patients with Major Depressive Disorder.Frontiers in psychiatry · 2018Article
- No association of a casein kinase 1ε (CK1ε) gene polymorphism with personality traits in healthy Chinese-Han subjects.Journal of molecular neuroscience : MN · 2012Article
- Association between a casein kinase 1 ε gene polymorphism and schizophrenia in a Chinese Han population.Journal of molecular neuroscience : MN · 2012Article
- Polymorphisms in ABLIM1 are associated with personality traits and alcohol dependence.Journal of molecular neuroscience : MN · 2012Article
- Association between DARPP-32 gene polymorphism and personality traits in healthy Chinese-Han subjects.Journal of molecular neuroscience : MN · 2011Article
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The Src family tyrosine kinase Fyn regulates a myriad of neurophysiological processes, including learning and memory. To date, the role of Fyn in the neurological mechanisms that determine personality traits has not been addressed. To this end, we determined the association between the rs706895C/T polymorphism of the Fyn gene (FYN) and personality traits measured by the Tridimensional Personality Questionnaire in 502 healthy Chinese-Han subjects. There were no significant differences in the total scores for novelty seeking (χ² = 5.12, P = 0.077), harm avoidance (HA; χ² = 2.63, P = 0.269), or reward dependence (RD; χ² = 3.94, P = 0.139) among the rs706895C/T genotypes. In sub-item analyses, however, both fear of uncertainty (HA2; χ² = 7.84, P = 0.020) and sentimentality (RD1; χ² = 8.27; P = 0.016) scores were significantly different among rs706895C/T genotypes. Our results suggest that FYN alleles can contribute to the variance in human personality traits.
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