Evidence map›Paper›PMID 21207080›Full record

ReviewJournal of neural transmission (Vienna, Austria : 1996)2011

The extracranial vascular theory of migraine: an artificial controversy.

Elliot Shevel

Registry-linked trialAbstract readReview
PubMed Publisher
In one paragraph

Review in Journal of neural transmission (Vienna, Austria : 1996), 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03026101 (Understanding the Role of the External Carotid Artery in the Pathophysiology of Migraine Pain), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03026101 naterminatednot on this mapstarted 2017, after this paper: background citation

Understanding the Role of the External Carotid Artery in the Pathophysiology of Migraine Pain

TypeinterventionalSponsorMontefiore Medical CenterRan2017 to 2025Enrolled4ConditionsMigraine Disorders, Migraine, Classic, Migraine Without AuraArmsNitroglycerin
3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Perivascular neurotransmitters: Regulation of cerebral blood flow and role in primary headaches.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2019
    Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Elliot ShevelThe Headache Clinic, 45 Empire Rd, Johannesburg, 2193, South Africa. drshevel@headclin.com

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Over the years there has been a considerable amount of controversy over whether the vascular component of migraine pain arises from the intracranial or the extracranial vessels, or both. Some have even questioned whether vasodilatation actually plays a significant role in migraine pain, and have described it as an unimportant epiphenomenon. The controversy is an artificial one though, which has been generated as a consequence of misrepresentation of the facts in the headache literature. In this review, some of the more blatant distortions in the literature are exposed.

Indexed as

AnimalsCarotid Artery, ExternalCerebrovascular CirculationHumansMigraine DisordersSkull

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.