Evidence map›Paper›PMID 21207045›Full record

ArticleClinical research in cardiology : official journal of the German Cardiac Society2011

Blood pressure management in a cohort of hypertensive patients in Germany treated by cardiologists.

Martin Thoenes, Ulrich Tebbe, Ludger Rosin, W Dieter Paar, Peter Bramlage, Wilhelm Kirch, Michael Böhm

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Article in Clinical research in cardiology : official journal of the German Cardiac Society, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Article
  3. Treating resistant hypertension: role of renal denervation.Integrated blood pressure control · 2013
    Review
  4. Assessment of serum cotinine in patients with chronic heart failure: self-reported versus objective smoking behaviour.Clinical research in cardiology : official journal of the German Cardiac Society · 2013
    Article
  5. Article
  6. Influence of algorithm-based analgesia and sedation in patients after sudden cardiac arrest.Clinical research in cardiology : official journal of the German Cardiac Society · 2012
    Article
  7. Treatment strategies for resistant arterial hypertension.Deutsches Arzteblatt international · 2011
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 1 country.

Martin ThoenesInstitute for Clinical Pharmacology, Medical Faculty Carl Gustav Carus, Technical University, Dresden, Germany.
Ulrich Tebbe
Ludger Rosin
W Dieter Paar
Peter Bramlage
Wilhelm Kirch
Michael Böhm
Sanofi (Germany) · DEUniversity Hospital Carl Gustav Carus · DEKlinikum Lippe · DEMahlo (Germany) · DESaarland University · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn Germany, an estimated 20-25 million patients suffer from hypertension. Blood pressure control rates are, however, lower than in many other European countries and the USA. The present analysis reports blood pressure treatment and control rates in Germany in patients with hypertension treated by cardiologists.

methodsThe present analysis reports data from a German subgroup analysis of a large, multinational, observational survey i-SEARCH that recruited patients in 2005/2006. It reports blood pressure readings, drug utilization and control rates in cardiology practice.

resultsA total of 4,982 patients were documented at 417 sites. Mean systolic/diastolic blood pressure (SBP/DBP) was 152 ± 19.5/88.4 ± 11.5 mmHg. SBP was 1.3 mmHg higher in men than in women (p = 0.021). The majority of patients had an SBP between 141 and 160 mmHg and 31.4% of patients had normal SBP. Overall blood pressure control rate was only 11.6% [95% CI 10.7-12.6] in treated patients. It was different in men [10.2%; 95% CI 9.0-11.6] than in women [8.1%; 95% CI 7.1-9.4; p = 0.008] and higher in patients without diabetes [12.7%; 95% CI 11.6-14.0] than in those with diabetes [4.3%; 95% CI 3.4-5.4; p < 0.0001]. One-third of patients received either monotherapy or dual therapy, or three and more drugs, respectively; 42.2% of patients received guideline-recommended dual combination therapy. A combination of beta-blockers + ACE inhibitors was most frequently prescribed (30.8%).

conclusionsOur data indicate a low level of blood pressure control, especially in patients at an increased risk for cardiovascular events, such as those with diabetes or cardiovascular comorbidities. Major efforts are required to improve hypertension management as recommend by current treatment guidelines.

Indexed as

Adrenergic beta-AntagonistsAgedAngiotensin-Converting Enzyme InhibitorsAntihypertensive AgentsBlood PressureCardiologyCardiovascular DiseasesCohort StudiesDiabetes ComplicationsDrug Therapy, CombinationFemaleGermanyHumansHypertensionMaleMiddle AgedAdrenergic beta-AntagonistsAngiotensin-Converting Enzyme InhibitorsAntihypertensive Agents

Identifiers

PMID21207045
OpenAlexW2085181031

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.