ArticleChild's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery2011
Transcranial Doppler can predict intracranial hypertension in children with severe traumatic brain injuries.
Article in Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06642896 (Quantitative Pupillometry in Brain Injury Children), which is not on this map. Cited by 26 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Quantitative Pupillometry in Brain Injury Children : Variation After Osmotherapy
Who cites it
26 citing papers in PubMed, 79 citations in OpenAlex.
- A pilot clinical study to estimate intracranial pressure utilising cerebral photoplethysmograms in traumatic brain injury patients.Acta neurochirurgica · 2024Trial
- Clinical Applications of Point-of-Care and Diagnostic Transcranial Doppler in the Pediatric Acute Care Setting: A Scoping Review.Neurocritical care · 2026Article
- Neuromonitoring in Children with Traumatic Brain Injury.Neurocritical care · 2024Review
- Optic nerve sheath diameter and pulsatility index for the diagnosis and follow-up in pediatric traumatic brain injury: a prospective observational cohort study.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2023Observational
- Associations between intracranial pressure thresholds and multimodal monitoring in acute traumatic neural injury: a scoping review.Acta neurochirurgica · 2023Article
- Cerebrovascular dynamics after pediatric traumatic brain injury.Frontiers in physiology · 2023Article
- Transcranial Doppler Ultrasound, a Review for the Pediatric Intensivist.Children (Basel, Switzerland) · 2022Review
- Transcranial Doppler in a child: A most valuable imaging modality.Ultrasound (Leeds, England) · 2022Article
- Evaluation of cerebral hemodynamics by transcranial Doppler ultrasonography and its correlation with intracranial pressure in an animal model of intracranial hypertension.Arquivos de neuro-psiquiatria · 2022Article
- Surgical treatment of post-infectious hydrocephalus in infants.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2021Article
- Practice Recommendations for Transcranial Doppler Ultrasonography in Critically Ill Children in the Pediatric Intensive Care Unit: A Multidisciplinary Expert Consensus Statement.Journal of pediatric intensive care · 2021Article
- Prehospital Detection of Life-Threatening Intracranial Pathology: An Unmet Need for Severe TBI in Austere, Rural, and Remote Areas.Frontiers in neurology · 2020Article
- Transcranial Doppler as a non-invasive method to estimate cerebral perfusion pressure in children with severe traumatic brain injury.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2020Article
- Transcranial Doppler in pediatric emergency and intensive care unit: a case series and literature review.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2018Review
- Non-invasive Monitoring of Intracranial Pressure Using Transcranial Doppler Ultrasonography: Is It Possible?Neurocritical care · 2016Review
- Intraoperative non invasive intracranial pressure monitoring during pneumoperitoneum: a case report and a review of the published cases and case report series.Journal of clinical monitoring and computing · 2016Review
- Non-invasive intracranial pressure assessment.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2016Review
- Pathophysiology and Treatment of Severe Traumatic Brain Injuries in Children.The Journal of neuroscience nursing : journal of the American Association of Neuroscience Nurses · 2016Article
- Doppler Non-invasive Monitoring of ICP in an Animal Model of Acute Intracranial Hypertension.Neurocritical care · 2015Article
- Reference values for cerebral blood flow velocities in critically ill, sedated children.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2015Article
Corrections and comments
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Authors and funding
8 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe purpose of this study is to evaluate the accuracy of emergency Transcranial Doppler (TCD) to predict intracranial hypertension and abnormal cerebral perfusion pressure in children with severe traumatic brain injury (TBI). PATIENTS AND
methodsA descriptive and retrospective cross-sectional study was designed through data collected from medical records of children with severe TBI (Glasgow coma scale ≤ 8), admitted to a level I pediatric trauma center, between January 2000 and December 2005. Early TCD examination was performed upon admission, and TCD profiles were considered as altered using previously validated threshold values for diastolic velocity (<25 cm/s) and pulsatility index (>1.31) or when no-flow/backflow was detected. Invasive intracranial pressure (ICP) and cerebral perfusion pressure (CPP) monitoring were considered as the gold standard to measure intracranial hypertension (ICH). Statistical analyses compared TCD profiles to increased ICP (≥ 20 mmHg) and abnormal cerebral perfusion pressure (<50 mmHg) at admission.
resultsNon-invasive TCD and ICP monitoring were performed in 117 severe head-injured children. Mean age was 7.6 ± 4.4 years, with a male prevalence (71%). Median initial Glasgow coma scale was 6. TCD had 94% of sensitivity to identify ICH at admission and a negative predict value of 95% to identify normal ICP at admission. Its sensitivity to predict abnormal cerebral perfusion pressure was 80%.
conclusionsThe high sensitivity of admission TCD to predict ICH and abnormal CPP after trauma demonstrates that TCD is an excellent first-line examination to determine those children who need urgent aggressive treatment and continuous invasive ICP monitoring.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.