ArticlePlant physiology2011
Concerted changes in gene expression and cell physiology of the cyanobacterium Synechocystis sp. strain PCC 6803 during transitions between nitrogen and light-limited growth.
Article in Plant physiology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed, 44 citations in OpenAlex.
- Coordination of Cyanobacterial Nitrate Assimilation and Photosynthesis by a Novel PsbO-Interacting Protein PirN.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Limiting factors in the operation of photosystems I and II in cyanobacteria.Microbial biotechnology · 2024Review
- A Comparison of the Effects of Continuous Illumination and Day/Night Regimes on PHB Accumulation inLife (Basel, Switzerland) · 2024Article
- Identification of a c-type heme oxygenase and its function during acclimation of cyanobacteria to nitrogen fluctuations.Communications biology · 2023Article
- Glucosidase Inhibitors Screening in Microalgae and Cyanobacteria Isolated from the Amazon and Proteomic Analysis of Inhibitor ProducingMicroorganisms · 2021Article
- Reconstruction of the absorption spectrum of Synechocystis sp. PCC 6803 optical mutants from the in vivo signature of individual pigments.Photosynthesis research · 2021Article
- Blue light induces major changes in the gene expression profile of the cyanobacterium Synechocystis sp. PCC 6803.Physiologia plantarum · 2020Article
- Comparative Targeted Proteomics of the Central Metabolism and Photosystems in SigE Mutant Strains ofMolecules (Basel, Switzerland) · 2018Article
- 6S RNA plays a role in recovery from nitrogen depletion in Synechocystis sp. PCC 6803.BMC microbiology · 2017Article
- Factors Altering Pyruvate Excretion in a Glycogen Storage Mutant of the Cyanobacterium, Synechococcus PCC7942.Frontiers in microbiology · 2016Article
- Daily transcriptome changes reveal the role of nitrogen in controlling microcystin synthesis and nutrient transport in the toxic cyanobacterium, Microcystis aeruginosa.BMC genomics · 2015Article
- Regulation of the scp Genes in the Cyanobacterium Synechocystis sp. PCC 6803--What is New?Molecules (Basel, Switzerland) · 2015Article
- Molecular investigation of the radiation resistance of edible cyanobacterium Arthrospira sp. PCC 8005.MicrobiologyOpen · 2015Article
- Phosphoproteome of the cyanobacterium Synechocystis sp. PCC 6803 and its dynamics during nitrogen starvation.Frontiers in microbiology · 2015Article
- Article
- GABA accumulation in response to different nitrogenous compounds in unicellular cyanobacterium Synechocystis sp. PCC 6803.Current microbiology · 2015Article
- Theoretical analysis of the cost of antagonistic activity for aquatic bacteria in oligotrophic environments.Frontiers in microbiology · 2015Article
- The gene sml0013 of Synechocystis species strain PCC 6803 encodes for a novel subunit of the NAD(P)H oxidoreductase or complex I that is ubiquitously distributed among Cyanobacteria.Plant physiology · 2013Article
- Integrated OMICS guided engineering of biofuel butanol-tolerance in photosynthetic Synechocystis sp. PCC 6803.Biotechnology for biofuels · 2013Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Physiological adaptation and genome-wide expression profiles of the cyanobacterium Synechocystis sp. strain PCC 6803 in response to gradual transitions between nitrogen-limited and light-limited growth conditions were measured in continuous cultures. Transitions induced changes in pigment composition, light absorption coefficient, photosynthetic electron transport, and specific growth rate. Physiological changes were accompanied by reproducible changes in the expression of several hundred open reading frames, genes with functions in photosynthesis and respiration, carbon and nitrogen assimilation, protein synthesis, phosphorus metabolism, and overall regulation of cell function and proliferation. Cluster analysis of the nearly 1,600 regulated open reading frames identified eight clusters, each showing a different temporal response during the transitions. Two large clusters mirrored each other. One cluster included genes involved in photosynthesis, which were up-regulated during light-limited growth but down-regulated during nitrogen-limited growth. Conversely, genes in the other cluster were down-regulated during light-limited growth but up-regulated during nitrogen-limited growth; this cluster included several genes involved in nitrogen uptake and assimilation. These results demonstrate complementary regulation of gene expression for two major metabolic activities of cyanobacteria. Comparison with batch-culture experiments revealed interesting differences in gene expression between batch and continuous culture and illustrates that continuous-culture experiments can pick up subtle changes in cell physiology and gene expression.
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