ArticleNeuron glia biology2010
Development of functional units within trigeminal ganglia correlates with increased expression of proteins involved in neuron-glia interactions.
Article in Neuron glia biology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 24 citations in OpenAlex.
- Review
- Comparative Electrophysiological Analysis of Trigeminal and Dorsal Root Ganglion Neurons in Mice.eNeuro · 2026Article
- A Fluorescence Imaging-Based 3D Analysis Pipeline for Mouse Trigeminal Ganglion Neurons.Biosensors · 2026Article
- Stellate Ganglia: A Key Therapeutic Target for Malignant Ventricular Arrhythmia in Heart Disease.Circulation research · 2025Review
- Article
- Making a head: Neural crest and ectodermal placodes in cranial sensory development.Seminars in cell & developmental biology · 2023Review
- Stellate Ganglia and Cardiac Sympathetic Overactivation in Heart Failure.International journal of molecular sciences · 2022Review
- Cross-talk signaling in the trigeminal ganglion: role of neuropeptides and other mediators.Journal of neural transmission (Vienna, Austria : 1996) · 2020Review
- Differences between Dorsal Root and Trigeminal Ganglion Nociceptors in Mice Revealed by Translational Profiling.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2019Article
- Age-Dependent Anti-migraine Effects of Valproic Acid and Topiramate in Rats.Frontiers in pharmacology · 2018Article
- Simple and reproducible approaches for the collection of select porcine ganglia.Journal of neuroscience methods · 2017Article
- The Molecular Fingerprint of Dorsal Root and Trigeminal Ganglion Neurons.Frontiers in molecular neuroscience · 2017Article
- How Far Have We Come in the Field of Nerve Regeneration After Trigeminal Nerve Injury?Current oral health reports · 2016Review
- Botulinum neurotoxin type A modulates vesicular release of glutamate from satellite glial cells.Journal of cellular and molecular medicine · 2015Article
- Modulation of inflammatory mediators in the trigeminal ganglion by botulinum neurotoxin type A: an organ culture study.The journal of headache and pain · 2015Article
- Satellite glial cell P2Y12 receptor in the trigeminal ganglion is involved in lingual neuropathic pain mechanisms in rats.Molecular pain · 2012Article
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Cell bodies of trigeminal nerves, which are located in the trigeminal ganglion, are completely surrounded by satellite glial cells and together form a functional unit that regulates neuronal excitability. The goals of this study were to investigate the cellular organization of the rat trigeminal ganglia during postnatal development and correlate those findings with expression of proteins implicated in neuron-glia interactions. During postnatal development there was an increase in the volume of the neuronal cell body, which correlated with a steady increase in the number of glial cells associated with an individual neuron from an average of 2.16 at birth to 7.35 on day 56 in young adults. Interestingly, while the levels of the inwardly rectifying K+ channel Kir4.1 were barely detectable during the first week, its expression in satellite glial cells increased by day 9 and correlated with initial formation of functional units. Similarly, expression of the vesicle docking protein SNAP-25 and neuropeptide calcitonin gene-related peptide was readily detected beginning on day 9 and remained elevated throughout postnatal development. Based on our findings, we propose that the expression of proteins involved in facilitating neuron-glia interactions temporally correlates with the formation of mature functional units during postnatal development of trigeminal ganglion.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.