Evidence map›Paper›PMID 21205046›Full record

ArticleAddiction (Abingdon, England)2011

Longitudinal association of preference-weighted health-related quality of life measures and substance use disorder outcomes.

Jeffrey M Pyne, Shanti Tripathi, Michael French, Kathryn McCollister, Richard C Rapp, Brenda M Booth

Abstract readValidation Study
In one paragraph

Article in Addiction (Abingdon, England), 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Substance Use Disorder Treatment Outcomes: Methodological Overview of Metrics and Criteria.International journal of methods in psychiatric research · 2025
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  11. Using the SF-6D to measure the impact of alcohol dependence on health-related quality of life.The European journal of health economics : HEPAC : health economics in prevention and care · 2015
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jeffrey M PyneCenter for Mental Healthcare and Outcomes Research, Central Arkansas Veterans Healthcare System, Little Rock, USA. jmpyne@uams.edu
Shanti Tripathi
Michael French
Kathryn McCollister
Richard C Rapp
Brenda M Booth

Funding

Reducing Barriers to Drug Abuse Treatment ServicesR01DA015690 · NIDA · WRIGHT STATE UNIVERSITY · PI RAPP, RICHARD CHARLES · 2003 to 2007
$4.0M
Economic Evaluation Methods: Development and ApplicationR01DA018645 · NIDA · UNIVERSITY OF MIAMI CORAL GABLES · PI FRENCH, MICHAEL T · 2005 to 2009
$3.0M
Cost-Effectiveness of Reducing Drug Treatment BarriersR01DA018980 · NIDA · UNIV OF ARKANSAS FOR MED SCIS · PI PYNE, JEFFREY M. · 2005 to 2008
$1.3M
Economic Consequences of Alcohol Use DisordersR01AA015695 · NIAAA · UNIVERSITY OF MIAMI CORAL GABLES · PI FRENCH, MICHAEL T · 2006 to 2008
$1.3M
Substance Abuse Treatment in Criminal Justice SettingsK01DA013962 · NIDA · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI MCCOLLISTER, KATHRYN E · 2004 to 2008
$597k
NIAAA NIH HHS R01 AA015695NIAAA NIH HHS R01 AA15695NIDA NIH HHS K01 DA013962NIDA NIH HHS K01 DA13962NIDA NIH HHS R01 DA015690NIDA NIH HHS R01 DA018645NIDA NIH HHS R01 DA018980NIDA NIH HHS R01 DA15690NIDA NIH HHS R01 DA18645NIDA NIH HHS R01 DA18980
6 · The paper itself

Abstract

aimTo examine the construct validity of generic preference-weighted health-related quality of life measures in a sample of patients with a substance use disorder (SUD).

designLongitudinal (baseline and 6-month follow-up) data from a research study that evaluated interventions to improve linkage and engagement with SUD treatment.

settingA central intake unit that referred patients to seven SUD treatment centers in a Midwestern US metropolitan area.

participantsA total of 495 individuals with a SUD. MEASUREMENTS: Participants completed two preference-weighted measures: the self-administered Quality of Well-Being scale (QWB-SA) and the standard gamble weighted Medical Outcomes Study SF-12 (SF-6D). They were also administered two clinical assessments: all seven domains of the Addiction Severity Index (ASI) and a symptom checklist based on the DSM-IV. Construct validity was determined via the relationships between disease-specific SUD and generic measures.

findingsIn unadjusted analyses, the QWB-SA and SF-6D change scores were correlated significantly with six ASI subscale change scores, but not with employment status. In adjusted repeated-measures analyses, three of seven ASI subscale scores were significant predictors of QWB-SA and 5/7 ASI subscale scores were significant predictors of SF-6D. Abstinence and problematic use at follow-up were significant predictors of QWB-SA and SF-6D. Effect sizes ranged from 0.352 to 0.400 for abstinence and -0.484 to -0.585 for problematic use.

conclusionsGeneric preference-weighted health-related quality of life measures show moderate to good associations with substance-use specific measures and in certain circumstances can be used in their stead. This study provides further support for the use of the Quality of Well-Being scale and Medical Outcomes Study SF-12 in clinical and economic evaluations of substance use disorder interventions.

Indexed as

Health StatusQuality of LifeAdolescentAdultCost-Benefit AnalysisData Interpretation, StatisticalDiagnostic and Statistical Manual of Mental DisordersFemaleHumansLongitudinal StudiesMaleOutcome Assessment, Health CarePatient Acceptance of Health CareQuality-Adjusted Life YearsSeverity of Illness IndexSubstance Abuse Treatment Centers

Identifiers

PMID21205046
PMCPMC3076048

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.