Evidence map›Paper›PMID 21203914›Full record

ReviewProtein & cell2010

Cilia in cell signaling and human disorders.

Neil A Duldulao, Jade Li, Zhaoxia Sun

Abstract readReview
In one paragraph

Review in Protein & cell, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Evolution of modular intraflagellar transport from a coatomer-like progenitor.Proceedings of the National Academy of Sciences of the United States of America · 2013
    Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Neil A DuldulaoDepartment of Genetics, Yale University School of Medicine, 333 Cedar St., SHM I-329A, New Haven, CT 06520, USA.
Jade Li
Zhaoxia Sun

Funding

Function of Ruvbl1-Ruvbl2 in dynein arm assembly in motile ciliated epithelial cellsR01HL175156 · NHLBI · YALE UNIVERSITY · PI ZHAOXIA SUN · 2024 to 2026
$2.1M
NHLBI NIH HHS R01 HL175156
6 · The paper itself

Abstract

One of the most widespread cellular organelles in nature is cilium, which is found in many unicellular and multicellular organisms. Formerly thought to be a mostly vestigial organelle, the cilium has been discovered in the past several decades to play critical motile and sensory roles involved in normal organogenesis during development. The role of cilia has also been implicated in an ever increasing array of seemingly unrelated human diseases, including blindness, kidney cysts, neural tube defects and obesity. In this article we review some of the recent developments in research on cilia, and how defects in ciliogenesis and function can give rise to developmental disorders and disease.

Indexed as

Signal TransductionAbnormalities, MultipleAnimalsCerebellar DiseasesCiliaFlagellaHedgehog ProteinsHumansModels, AnimalPolycystic Kidney DiseasesProtein TransportWnt ProteinsHedgehog ProteinsWnt Proteins

Identifiers

PMID21203914
PMCPMC4875200

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.