Evidence map›Paper›PMID 21203801›Full record

ArticleEuropean journal of epidemiology2011

Individual accumulation of heterogeneous risks explains perinatal inequalities within deprived neighbourhoods.

Sarah Timmermans, Gouke J Bonsel, Régine P M Steegers-Theunissen, Johan P Mackenbach, Ewout W Steyerberg, Hein Raat, Henri A Verbrugh, Henning W Tiemeier, Albert Hofman, Erwin Birnie and 3 more

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In one paragraph

Article in European journal of epidemiology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 52 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
52citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

52 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Deprived areas and adverse perinatal outcome: a systematic review.Archives of gynecology and obstetrics · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Sarah TimmermansThe Generation R Study Group, Erasmus MC Rotterdam, POB 2040, 3000 CA Rotterdam, The Netherlands. s.timmermans@erasmusmc.nl
Gouke J Bonsel
Régine P M Steegers-Theunissen
Johan P Mackenbach
Ewout W Steyerberg
Hein Raat
Henri A Verbrugh
Henning W Tiemeier
Albert Hofman
Erwin Birnie
Caspar W N Looman
Vincent W V Jaddoe
Eric A P Steegers

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dutch' figures on perinatal mortality and morbidity are poor compared to EU-standards. Considerable within-country differences have been reported too, with decreased perinatal health in deprived urban areas. We investigated associations between perinatal risk factors and adverse perinatal outcomes in 7,359 pregnant women participating in population-based prospective cohort study, to establish the independent role, if any, for living within a deprived urban neighbourhood. Main outcome measures included perinatal death, intrauterine growth restriction (IUGR), prematurity, congenital malformations, Apgar at 5 min < 7, and pre-eclampsia. Information regarding individual risk factors was obtained from questionnaires, physical examinations, ultrasounds, biological samples, and medical records. The dichotomous Dutch deprivation indicator was additionally used to test for unexplained deprived urban area effects. Pregnancies from a deprived neighbourhood had an increased risk for perinatal death (RR 1.8, 95% CI [1.1; 3.1]). IUGR, prematurity, Apgar at 5 min < 7, and pre-eclampsia also showed higher prevalences (P < 0.05). Residing within a deprived neighbourhood was associated with increased prevalence of all measured risk factors. Regression analysis showed that the observed neighbourhood related differences in perinatal outcomes could be attributed to the increased risk factor prevalence only, without a separated role for living within a deprived neighbourhood. Women from a deprived neighbourhood had significantly more 'possibly avoidable' risk factors. To conclude, women from a socioeconomically deprived neighbourhood are at an increased risk for adverse pregnancy outcomes. Differences regarding possibly avoidable risk factors imply that preventive strategies may prove effective.

Indexed as

Health Status DisparitiesPoverty AreasAdultApgar ScoreCohort StudiesCongenital AbnormalitiesFemaleFetal Growth RetardationHumansInfant, NewbornNetherlandsPerinatal MortalityPre-EclampsiaPregnancyPregnancy OutcomePremature Birth

Identifiers

PMID21203801
PMCPMC3043261

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.