ReviewAnnals of botany2011
Elucidating the functional role of endoreduplication in tomato fruit development.
Review in Annals of botany, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers.
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Who cites it
46 citing papers in PubMed, 143 citations in OpenAlex.
- Expression dynamics of starch and proanthocyanidin biosynthesis genes during Quercus glauca fruit development.BMC plant biology · 2026Article
- Comparative transcriptomics among peach, almond and their interspecific F1 hybrid reveal key common and species-specific regulatory pathways involved in fruit development.BMC plant biology · 2026Article
- Compound Inflorescence (S) represses fruit growth and seed development in tomato.Molecular horticulture · 2026Article
- Identification and functional evaluation of cyclin-dependent kinase genes reveals that CDKB1;1 and CDKB2;2 contribute to the balance of mitosis and endoreduplication in Medicago truncatula nodule.BMC plant biology · 2025Article
- Light signal regulates endoreduplication and tomato fruit expansion through the SlPIF1a-SlTLFP8-SlCDKB2 module.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Physiological DNA damage promotes functional endoreplication of mammary gland alveolar cells during lactation.Nature communications · 2024Article
- Variations in Fruit Ploidy Level and Cell Size between Small- and Large-Fruited Olive Cultivars during Fruit Ontogeny.Plants (Basel, Switzerland) · 2024Article
- Ammonium treatment inhibits cell cycle activity and induces nuclei endopolyploidization in Arabidopsis thaliana.Planta · 2024Article
- Functional consequences of somatic polyploidy in development.Development (Cambridge, England) · 2024Review
- The SIAMESE family of cell-cycle inhibitors in the response of plants to environmental stresses.Frontiers in plant science · 2024Review
- Local endoreduplication of the host is a conserved process during Phytomyxea-host interaction.Frontiers in microbiology · 2024Article
- The ORGAN SIZE (ORG) locus modulates both vegetative and reproductive gigantism in domesticated tomato.Annals of botany · 2023Article
- Endoreplication-Why Are We Not Using Its Full Application Potential?International journal of molecular sciences · 2023Review
- Characterization of Transcriptome Dynamics during Early Fruit Development in Olive (International journal of molecular sciences · 2023Article
- What makes a giant fruit? Assembling a genomic toolkit underlying various fruit traits of the mammoth group ofFrontiers in genetics · 2022Article
- Characterization of 15-Plants (Basel, Switzerland) · 2021Article
- Fruit size control by a zinc finger protein regulating pericarp cell size in tomato.Molecular horticulture · 2021Article
- Melatonin Application Modifies Antioxidant Defense and Induces Endoreplication in Maize Seeds Exposed to Chilling Stress.International journal of molecular sciences · 2021Article
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Corrections and comments
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Authors and funding
9 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundEndoreduplication is the major source of endopolyploidy in higher plants. The process of endoreduplication results from the ability of cells to modify their classical cell cycle into a partial cell cycle where DNA synthesis occurs independently from mitosis. Despite the ubiquitous occurrence of the phenomenon in eukaryotic cells, the physiological meaning of endoreduplication remains vague, although several roles during plant development have been proposed, mostly related to cell differentiation and cell size determination. SCOPE: Here recent advances in the knowledge of endoreduplication and fruit organogenesis are reviewed, focusing on tomato (Solanum lycopersicum) as a model, and the functional analyses of endoreduplication-associated regulatory genes in tomato fruit are described.
conclusionsThe cyclin-dependent kinase inhibitory kinase WEE1 and the anaphase promoting complex activator CCS52A both participate in the control of cell size and the endoreduplication process driving cell expansion during early fruit development in tomato. Moreover the fruit-specific functional analysis of the tomato CDK inhibitor KRP1 reveals that cell size and fruit size determination can be uncoupled from DNA ploidy levels, indicating that endoreduplication acts rather as a limiting factor for cell growth. The overall functional data contribute to unravelling the physiological role of endoreduplication in growth induction of fleshy fruits.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.