ArticleThe European journal of neuroscience2011
Somatosensory inputs modify auditory spike timing in dorsal cochlear nucleus principal cells.
Article in The European journal of neuroscience, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
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Who cites it
32 citing papers in PubMed, 57 citations in OpenAlex.
- Review
- Tinnitus-like "hallucinations" elicited by sensory deprivation in an entropy maximization recurrent neural network.PLoS computational biology · 2021Article
- Sensory feedback-dependent coding of arm position in local field potentials of the posterior parietal cortex.Scientific reports · 2021Article
- Audiotactile interactions in the mouse cochlear nucleus.Scientific reports · 2021Article
- Bimodal Auditory Electrical Stimulation for the Treatment of Tinnitus: Preclinical and Clinical Studies.Current topics in behavioral neurosciences · 2021Article
- Unisensory and Multisensory Responses in Fetal Alcohol Spectrum Disorders (FASD): Effects of Spatial Congruence.Neuroscience · 2020Article
- Cross-Talk of Low-Level Sensory and High-Level Cognitive Processing: Development, Mechanisms, and Relevance for Cross-Modal Abilities of the Brain.Frontiers in neurorobotics · 2020Review
- Multisensory activation of ventral cochlear nucleus D-stellate cells modulates dorsal cochlear nucleus principal cell spatial coding.The Journal of physiology · 2018Article
- Multisensory Integration Enhances Temporal Coding in Ventral Cochlear Nucleus Bushy Cells.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2018Article
- Tinnitus: Maladaptive auditory-somatosensory plasticity.Hearing research · 2016Review
- Spontaneous Activity Defines Effective Convergence Ratios in an Inhibitory Circuit.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2016Article
- Multisensory Interactions Influence Neuronal Spike Train Dynamics in the Posterior Parietal Cortex.PloS one · 2016Article
- Bimodal stimulus timing-dependent plasticity in primary auditory cortex is altered after noise exposure with and without tinnitus.Journal of neurophysiology · 2015Article
- Effects of acoustic trauma on the auditory system of the rat: The role of microglia.Neuroscience · 2015Article
- The Structural Development of the Mouse Dorsal Cochlear Nucleus.Journal of the Association for Research in Otolaryngology : JARO · 2015Article
- Listening to another sense: somatosensory integration in the auditory system.Cell and tissue research · 2015Review
- Investigating a new neuromodulation treatment for brain disorders using synchronized activation of multimodal pathways.Scientific reports · 2015Article
- Article
- Synaptic mechanisms for generating temporal diversity of auditory representation in the dorsal cochlear nucleus.Journal of neurophysiology · 2015Article
- Transcutaneous induction of stimulus-timing-dependent plasticity in dorsal cochlear nucleus.Frontiers in systems neuroscience · 2015Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
In addition to auditory inputs, dorsal cochlear nucleus (DCN) pyramidal cells in the guinea pig receive and respond to somatosensory inputs and perform multisensory integration. DCN pyramidal cells respond to sounds with characteristic spike-timing patterns that are partially controlled by rapidly inactivating potassium conductances. Deactivating these conductances can modify both spike rate and spike timing of responses to sound. Somatosensory pathways are known to modify response rates to subsequent acoustic stimuli, but their effect on spike timing is unknown. Here, we demonstrate that preceding tonal stimulation with spinal trigeminal nucleus (Sp5) stimulation significantly alters the first spike latency, the first interspike interval and the average discharge regularity of firing evoked by the tone. These effects occur whether the neuron is excited or inhibited by Sp5 stimulation alone. Our results demonstrate that multisensory integration in DCN alters spike-timing representations of acoustic stimuli in pyramidal cells. These changes likely occur through synaptic modulation of intrinsic excitability or synaptic inhibition.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.