ReviewImmunological reviews2011
Immunogenomics and systems biology of vaccines.
Review in Immunological reviews, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
32 citing papers in PubMed, 76 citations in OpenAlex.
- Trial
- Multi-epitope vaccine candidates based on mycobacterial membrane protein large (MmpL) proteins againstOpen biology · 2023Article
- The power of phages: revolutionizing cancer treatment.Frontiers in oncology · 2023Review
- Potential Application of Exosomes in Vaccine Development and Delivery.Pharmaceutical research · 2022Review
- Analyzing the Systems Biology Effects of COVID-19 mRNA Vaccines to Assess Their Safety and Putative Side Effects.Pathogens (Basel, Switzerland) · 2022Article
- Racing to immunity: Journey to a COVID-19 vaccine and lessons for the future.British journal of clinical pharmacology · 2021Review
- Systems Biology Analysis of the Radiation-Attenuated Schistosome Vaccine Reveals a Role for Growth Factors in Protection and Hemostasis Inhibition in Parasite Survival.Frontiers in immunology · 2021Article
- RNA Sequencing (RNA-Seq) Based Transcriptome Analysis in Immune Response of Holstein Cattle to Killed Vaccine against Bovine Viral Diarrhea Virus Type I.Animals : an open access journal from MDPI · 2020Article
- The Role of Nanomaterials in the Treatment of Diseases and Their Effects on the Immune System.Open access Macedonian journal of medical sciences · 2019Review
- Review
- Exploitation ofFrontiers in immunology · 2019Review
- Cytokine production in whole-blood cultures following immunization with an influenza vaccine.Human vaccines & immunotherapeutics · 2018Article
- Safety and efficiency of active immunization with detoxified antigen against scorpion venom: side effect evaluation.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2017Article
- Molecular and genetic inflammation networks in major human diseases.Molecular bioSystems · 2016Review
- Review
- Modular expression analysis reveals functional conservation between human Langerhans cells and mouse cross-priming dendritic cells.The Journal of experimental medicine · 2015Article
- An Enriched European Eel Transcriptome Sheds Light upon Host-Pathogen Interactions with Vibrio vulnificus.PloS one · 2015Article
- An Overview of Challenges Limiting the Design of Protective Mucosal Vaccines for Finfish.Frontiers in immunology · 2015Review
- The future potential for cocaine vaccines.Expert opinion on biological therapy · 2014Review
- Systems vaccinology: probing humanity's diverse immune systems with vaccines.Proceedings of the National Academy of Sciences of the United States of America · 2014Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 2 countries.
Funding
Abstract
Vaccines represent a potent tool to prevent or contain infectious diseases with high morbidity or mortality. However, despite their widespread use, we still have a limited understanding of the mechanisms underlying the effective elicitation of protective immune responses by vaccines. Recent research suggests that this represents the cooperative action of the innate and adaptive immune systems. Immunity is made of a multifaceted set of integrated responses involving a dynamic interaction of thousands of molecules, whose list is constantly updated to fill the several empty spaces of this puzzle. The recent development of new technologies and computational tools permits the comprehensive and quantitative analysis of the interactions between all of the components of immunity over time. Here, we review the role of the innate immunity in the host response to vaccine antigens and the potential of systems biology in providing relevant and novel insights in the mechanisms of action of vaccines to improve their design and effectiveness.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.