Evidence map›Paper›PMID 21197542›Full record

Trial reportEuropean journal of applied physiology2011

Effects of bicarbonate ingestion and high intensity exercise on lactate and H(+)-ion distribution in different blood compartments.

Christoph Zinner, Patrick Wahl, Silvia Achtzehn, Billy Sperlich, Joachim Mester

Abstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in European journal of applied physiology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Trial
  5. Trial
  6. Article
  7. Article
  8. Review
  9. The Impact of Hyperoxia on Human Performance and Recovery.Sports medicine (Auckland, N.Z.) · 2017
    Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Christoph ZinnerInstitute of Training Science and Sport Informatics, German Sport University Cologne, Am Sportpark Müngersdorf 6, 50933, Cologne, Germany. zinner@dshs-koeln.de
Patrick Wahl
Silvia Achtzehn
Billy Sperlich
Joachim Mester

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lactate (La) and H(+)-ions are unequally distributed in the blood between plasma and red blood cells (RBCs). To our knowledge there is no data concerning the effects of an oral ingestion of bicarbonate (HCO(3) (-)) on repeated high intensity sprint exercise and La and H(+) distribution between plasma and RBCs. Since an oral ingestion of HCO(3) (-) leads to a higher efflux of La from the working skeletal muscle to the plasma, as it was shown by previous studies, this would lead to a higher gradient of La between plasma and RBCs. Although a higher gradient leads to a higher uptake, it is even more difficult for the RBCs to take up La fast enough, due to the more stressed transport system. Since RBCs function to transport La from the working muscle and help to maintain a concentration difference between plasma and muscle, this potentially increases performance during repeated sprint exercise (e.g. 4 × 30 s). The major goal of the present investigation was to test this hypothesis. 11 male participants ingested either a solution of sodium bicarbonate (NaHCO(3)) or placebo (CaCO(3)). Thereafter all performed four maximal 30 s sprints with 5 min of passive rest. During the resting periods concentrations of HCO(3) (-), La and H(+) where measured in both blood compartments (plasma and RBCs). There were no significant differences in the La-ratios between plasma and RBCs between both interventions. These results indicate that the La/H(+) co-transport is not affected by an oral ingestion on NaHCO(3).

Indexed as

Administration, OralAdultEatingErythrocytesExerciseExercise TestHumansHydrogenLactic AcidMalePlacebosProtonsSerumSodium BicarbonateYoung AdultHydrogenLactic AcidPlacebosProtonsSodium Bicarbonate

Identifiers

PMID21197542

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.