ArticleClinical & developmental immunology2011
Clustering of Mycobacterium tuberculosis cases in Acapulco: Spoligotyping and risk factors.
Article in Clinical & developmental immunology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
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Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it, 37 citations in OpenAlex.
- Methods used in the spatial analysis of tuberculosis epidemiology: a systematic review.BMC medicine · 2018Pooled it
- Molecular Epidemiology ofMicroorganisms · 2025Review
- Genetic Diversity ofPathogens (Basel, Switzerland) · 2024Article
- Genetic Diversity ofFrontiers in cellular and infection microbiology · 2022Article
- Genetic diversity and drug susceptibility of Mycobacterium tuberculosis in a city with a high prevalence of drug resistant tuberculosis from Southeast of Mexico.BMC infectious diseases · 2021Article
- Detailed epidemiological analysis as a strategy for evaluating the actual behavior of tuberculosis in an apparently low-incidence region.Pathogens and global health · 2020Article
- Circulation ofPathogens and global health · 2019Review
- Review
- Genetic diversity of drug and multidrug-resistant Mycobacterium tuberculosis circulating in Veracruz, Mexico.PloS one · 2018Article
- Article
- Prevalence and occurrence rate of Mycobacterium tuberculosis Haarlem family multi-drug resistant in the worldwide population: A systematic review and meta-analysis.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2015Review
- Article
- Comparative Mycobacterium tuberculosis spoligotype distribution in Mexico.Journal of clinical microbiology · 2014Article
- Molecular assessment, drug-resistant profile, and spacer oligonucleotide typing (spoligotyping) of Mycobacterium tuberculosis strains from Tamaulipas, México.Journal of clinical laboratory analysis · 2014Article
- Characterisation of pks15/1 in clinical isolates of Mycobacterium tuberculosis from Mexico.Memorias do Instituto Oswaldo Cruz · 2013Article
- Genetic diversity of the Mycobacterium tuberculosis complex in San Luis Potosí, México.BMC research notes · 2013Article
- Spatial and temporal distribution of tuberculosis in the State of Mexico, Mexico.TheScientificWorldJournal · 2012Article
- Mycobacterium tuberculosis Complex Genotype Diversity and Drug Resistance Profiles in a Pediatric Population in Mexico.Tuberculosis research and treatment · 2011Article
Corrections and comments
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Authors and funding
10 authors at 4 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Recurrence and reinfection of tuberculosis have quite different implications for prevention. We identified 267 spoligotypes of Mycobacterium tuberculosis from consecutive tuberculosis patients in Acapulco, Mexico, to assess the level of clustering and risk factors for clustered strains. Point cluster analysis examined spatial clustering. Risk analysis relied on the Mantel Haenszel procedure to examine bivariate associations, then to develop risk profiles of combinations of risk factors. Supplementary analysis of the spoligotyping data used SpolTools. Spoligotyping identified 85 types, 50 of them previously unreported. The five most common spoligotypes accounted for 55% of tuberculosis cases. One cluster of 70 patients (26% of the series) produced a single spoligotype from the Manila Family (Clade EAI2). The high proportion (78%) of patients infected with cluster strains is compatible with recent transmission of TB in Acapulco. Geomatic analysis showed no spatial clustering; clustering was associated with a risk profile of uneducated cases who lived in single-room dwellings. The Manila emerging strain accounted for one in every four cases, confirming that one strain can predominate in a hyperendemic area.
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