Evidence map›Paper›PMID 21197076›Full record

ReviewInfectious diseases in obstetrics and gynecology2010

Recent advances in understanding the microbiology of the female reproductive tract and the causes of premature birth.

Xia Zhou, Rebecca M Brotman, Pawel Gajer, Zaid Abdo, Ursel Schüette, Sam Ma, Jacques Ravel, Larry J Forney

Open access · hybridAbstract readReview
In one paragraph

Review in Infectious diseases in obstetrics and gynecology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed, 1 pooled it
6.5field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 1 synthesis or guideline pooled it, 80 citations in OpenAlex.

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  16. A new anti-microbial combination prolongs the latency period, reduces acute histologic chorioamnionitis as well as funisitis, and improves neonatal outcomes in preterm PROM.The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians · 2016
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Xia ZhouInitiative for Bioinformatics and Evolutionary Studies, University of Idaho, Moscow, ID 83844-3051, USA.
Rebecca M Brotman
Pawel Gajer
Zaid Abdo
Ursel Schüette
Sam Ma
Jacques Ravel
Larry J Forney
University of Idaho · USUniversity of Maryland, Baltimore · US

Funding

Genomic Tools For Studying The Ecology Of The Human Vaginal MicrofloraU01AI070921 · NIAID · UNIVERSITY OF MARYLAND BALTIMORE · PI RAVEL, JACQUES · 2006 to 2010
$4.0M
The Microbial Ecology of Bacterial Vaginosis: A Fine Scale Resolution MetagenomicUH2AI083264 · NIAID · UNIVERSITY OF MARYLAND BALTIMORE · PI RAVEL, JACQUES · 2009 to 2011
$1.9M
Molecular Epidemiology of the Vaginal MicrobiomeK01AI080974 · NIAID · UNIVERSITY OF MARYLAND BALTIMORE · PI BROTMAN, REBECCA M. · 2010 to 2014
$644k
NIAID NIH HHS 1UH2AI083264NIAID NIH HHS 1UO1AI070921NIAID NIH HHS K01 AI080974NIAID NIH HHS U01 AI070921NIAID NIH HHS UH2 AI083264PHS HHS KO1-A1080974
6 · The paper itself

Abstract

Data derived from molecular microbiological investigations of the human vagina have led to the discovery of resident bacterial communities that exhibit marked differences in terms of species composition. All undergo dynamic changes that are likely due to intrinsic host and behavioral factors. Similar types of bacteria have been found in both amniotic fluid and the vagina, suggesting a potential route of colonization. Given that not all of the species involved in intrauterine infections are readily cultivated, it is important that culture-independent methods of analysis must be used to understand the etiology of these infections. Further research is needed to establish whether an ascending pathway from the vagina to the amniotic cavity enables the development of intrauterine infections.

Indexed as

Amniotic FluidFemaleHumansMetagenomePregnancyPregnancy Complications, InfectiousPremature BirthRNA, Ribosomal, 16SSequence Analysis, RNATime FactorsUterusVaginaVaginosis, BacterialRNA, Ribosomal, 16S

Identifiers

PMID21197076
PMCPMC3004384
OpenAlexW1987600121

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.