Evidence map›Paper›PMID 21197025›Full record

ArticleOptics express2010

Holographic opto-fluidic microscopy.

Waheb Bishara, Hongying Zhu, Aydogan Ozcan

Abstract read
In one paragraph

Article in Optics express, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed.

  1. Review
  2. Article
  3. Fluid Flow Measurements in Nanoslits Using Holographic Microscopy.Langmuir : the ACS journal of surfaces and colloids · 2025
    Article
  4. Article
  5. Review
  6. Review
  7. Review
  8. Article
  9. Article
  10. Review
  11. Article
  12. Microfluidic Based Optical Microscopes on Chip.Cytometry. Part A : the journal of the International Society for Analytical Cytology · 2018
    Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Tomographic flow cytometry by digital holography.Light, science & applications · 2017
    Article
  18. Article
  19. Quasi noise-free digital holography.Light, science & applications · 2016
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Waheb BisharaElectrical Engineering Department, University of California, Los Angeles, CA 90095, USA. bishara@ucla.edu
Hongying Zhu
Aydogan Ozcan

Funding

Towards Mega-Throughput, Label-free Genomics and Proteomics: Revolutionizing MicrDP2OD006427 · OD · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI OZCAN, AYDOGAN · 2009 to 2009
$2.3M
Lensfree On-Chip Near-field Microscopy based on Resonant Nano-AperturesR21EB009222 · NIBIB · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI OZCAN, AYDOGAN · 2008 to 2009
$330k
NIBIB NIH HHS 1R21EB009222-01NIBIB NIH HHS R21 EB009222NIH HHS DP2 OD006427NIH HHS DP2OD006427
6 · The paper itself

Abstract

Over the last decade microfluidics has created a versatile platform that has significantly advanced the ways in which micro-scale organisms and objects are controlled, processed and investigated, by improving the cost, compactness and throughput aspects of analysis. Microfluidics has also expanded into optics to create reconfigurable and flexible optical devices such as reconfigurable lenses, lasers, waveguides, switches, and on-chip microscopes. Here we present a new opto-fluidic microscopy modality, i.e., Holographic Opto-fluidic Microscopy (HOM), based on lensless holographic imaging. This imaging modality complements the miniaturization provided by microfluidics and would allow the integration of microscopy into existing on-chip microfluidic devices with various functionalities. Our imaging modality utilizes partially coherent in-line holography and pixel super-resolution to create high-resolution amplitude and phase images of the objects flowing within micro-fluidic channels, which we demonstrate by imaging C. elegans, Giardia lamblia, and Mulberry pollen. HOM does not involve complicated fabrication processes or precise alignment, nor does it require a highly uniform flow of objects within microfluidic channels.

Indexed as

LensesEquipment DesignEquipment Failure AnalysisImage EnhancementMicrofluidicsMicroscopyMiniaturization

Identifiers

PMID21197025
PMCPMC3057885

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.