Evidence map›Paper›PMID 21196177›Full record

ReviewFrontiers in bioscience (Landmark edition)2011

Molecular imaging metrics to evaluate response to preclinical therapeutic regimens.

R Adam Smith, Saffet Guleryuz, H Charles Manning

Abstract readReview
In one paragraph

Review in Frontiers in bioscience (Landmark edition), 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

R Adam SmithVanderbilt University Institute of Imaging Science, Vanderbilt University Medical enter, Nashville, TN 37232, USA.
Saffet Guleryuz
H Charles Manning

Funding

Biological Basis of Imaging Biomarkers in Colorectal CancerR01CA140628 · NCI · VANDERBILT UNIVERSITY · PI MANNING, HENRY CHARLES · 2009 to 2013
$1.5M
Molecular Determinants Affecting FLT-PET in Colorectal CancerRC1CA145138 · NCI · VANDERBILT UNIVERSITY · PI MANNING, HENRY CHARLES · 2009 to 2010
$998k
Synergizing Quantitative HTS Technologies to Guide MIA Discovery and DevelopmentK25CA127349 · NCI · VANDERBILT UNIVERSITY · PI MANNING, HENRY CHARLES · 2008 to 2012
$709k
NCI NIH HHS K25 CA127349NCI NIH HHS R01 CA140628NCI NIH HHS RC1 CA145138
6 · The paper itself

Abstract

Molecular imaging comprises a range of techniques, spanning not only several imaging modalities but also many disease states and organ sites. While advances in new technology platforms have enabled a deeper understanding of the cellular and molecular basis of malignancy, reliable non-invasive imaging metrics remain an important tool for both diagnostics and patient management. Furthermore, the non- invasive nature of molecular imaging can overcome shortcomings associated with traditional biological approaches and provide valuable information relevant to patient care. Integration of information from multiple imaging techniques has the potential to provide a more comprehensive understanding of specific tumor characteristics, tumor status, and treatment response.

Indexed as

Diagnostic ImagingDideoxynucleosidesFluorodeoxyglucose F18HumansMolecular ImagingNeoplasmsNeovascularization, PathologicPositron-Emission TomographyThymidine KinasealovudineDideoxynucleosidesFluorodeoxyglucose F18Thymidine Kinase

Identifiers

PMID21196177
PMCPMC3023459

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.