ArticleJournal of the American Veterinary Medical Association2011
Sickness behaviors in response to unusual external events in healthy cats and cats with feline interstitial cystitis.
Article in Journal of the American Veterinary Medical Association, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 70 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
70 citing papers in PubMed, 5 syntheses or guidelines pooled it, 169 citations in OpenAlex.
- 2025 iCatCare consensus guidelines on the diagnosis and management of lower urinary tract diseases in cats.Journal of feline medicine and surgery · 2025Guideline
- 2015 AAHA/AAFP pain management guidelines for dogs and cats.Journal of feline medicine and surgery · 2015Guideline
- AAFP and ISFM feline-friendly nursing care guidelines.Journal of feline medicine and surgery · 2012Guideline
- WSAVA nutritional assessment guidelines.Journal of feline medicine and surgery · 2011Guideline
- AAFP and ISFM feline-friendly handling guidelines.Journal of feline medicine and surgery · 2011Guideline
- Feline chronic diarrhea: causes and nutritional management.Veterinary and animal science · 2026Review
- Assessing Animal Welfare and Service Needs in a Community-Based Program.Animals : an open access journal from MDPI · 2026Article
- Serum and Urine Nerve Growth Factor and Glycosaminoglycan Levels in Obstructive and Non-Obstructive Feline Urolithiasis and Interstitial Cystitis.Veterinary medicine and science · 2026Article
- Resolution of Chronic Diarrhoea Following Treatment of Periodontal Disease in a Cat.Animals : an open access journal from MDPI · 2026Article
- Low-dose radiation therapy for idiopathic or interstitial cystitis in male cats.Journal of veterinary internal medicine · 2026Article
- Exploring kitten socialisation practices and welfare implications within a Swedish breeding association.Animal welfare (South Mimms, England) · 2026Article
- Sustained improvements in human-cat interaction in the shelter sector: a study of a best-practice educational intervention.Frontiers in veterinary science · 2026Article
- Neutrophil-to-Lymphocyte Ratio as a Promising Non-Invasive Biomarker for Diagnosis of Feline Idiopathic Cystitis in Cats.Animals : an open access journal from MDPI · 2025Article
- RETRACTED: Hair Cortisol and Fe-BARQ: Evaluating Chronic Stress and Behavior in Cats with Chronic Kidney Disease.Animals : an open access journal from MDPI · 2025Article
- Pandemic predisposing influence for feline lower urinary disorders.Frontiers in veterinary science · 2025Article
- Tools for the Approach of Fear, Anxiety, and Stress in the Domestic Feline: An Update.Veterinary medicine international · 2025Review
- Effects of an antimicrobial peptide on transport- and novel environment-induced stress in British Shorthair cats.Frontiers in veterinary science · 2025Article
- Hair cortisol concentrations in clipped and combed hair and associations with characteristics, health status and stress in domestic cats.Scientific reports · 2024Article
- Interstitial cystitis-an imbalance of risk and protective factors?Frontiers in pain research (Lausanne, Switzerland) · 2024Review
- Incidence of feline idiopathic cystitis and urethral obstruction during COVID-19 human movement restrictions in Queensland, Australia.Journal of feline medicine and surgery · 2023Article
10 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
objectiveTo compare sickness behaviors (SB) in response to unusual external events (UEE) in healthy cats with those of cats with feline interstitial cystitis (FIC).
designProspective observational study. ANIMALS: 12 healthy cats and 20 donated cats with FIC. PROCEDURES: Cats were housed in a vivarium. Sickness behaviors referable to the gastrointestinal and urinary tracts, the skin, and behavior problems were recorded by a single observer for 77 weeks. Instances of UEE (eg, changes in caretakers, vivarium routine, and lack of interaction with the investigator) were identified during 11 of the 77 weeks. No instances of UEE were identified during the remaining 66 weeks, which were considered control weeks.
resultsAn increase in age and exposure to UEE, but not disease status, significantly increased total number of SB when results were controlled for other factors. Evaluation of individual SB revealed a protective effect of food intake for healthy males. An increase in age conferred a small increase in relative risk (RR) for upper gastrointestinal tract signs (RR, 1.2) and avoidance behavior (1.7). Exposure to UEE significantly increased the RR for decreases in food intake (RR, 9.3) and for no eliminations in 24 hours (6.4). Exposure to UEE significantly increased the RR for defecation (RR, 9.8) and urination (1.6) outside the litter box. CONCLUSIONS AND CLINICAL RELEVANCE: SB, including some of the most commonly observed abnormalities in client-owned cats, were observed after exposure to UEE in both groups. Because healthy cats and cats with FIC were comparably affected by UEE, clinicians should consider the possibility of exposure to UEE in cats evaluated for these signs.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.