ReviewJournal of Zhejiang University. Science. B2011
Whole genome amplification in preimplantation genetic diagnosis.
Review in Journal of Zhejiang University. Science. B, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed.
- Article
- Whole Genomic Amplification for Detecting Single-Gene Variants Causing Inherited Disease.Methods in molecular biology (Clifton, N.J.) · 2026Article
- Primary hepatic follicular dendritic cell sarcoma: A case study and literature review.The Journal of international medical research · 2025Review
- How is Excitotoxicity Being Modelled in iPSC-Derived Neurons?Neurotoxicity research · 2024Review
- The first clinical validation of whole-genome screening on standard trophectoderm biopsies of preimplantation embryos.F&S reports · 2024Article
- Embryo biopsies for genomic selection in tropical dairy cattle.Animal reproduction · 2023Review
- Disposable DNA Amplification Chips with Integrated Low-Cost Heaters.Micromachines · 2020Article
- Performance comparison of two whole genome amplification techniques in frame of multifactor preimplantation genetic testing.Journal of assisted reproduction and genetics · 2018Article
- STR profiling and Copy Number Variation analysis on single, preserved cells using current Whole Genome Amplification methods.Scientific reports · 2017Article
- Microfluidics for genome-wide studies involving next generation sequencing.Biomicrofluidics · 2017Review
- Workflow optimization of whole genome amplification and targeted panel sequencing for CTC mutation detection.NPJ genomic medicine · 2017Article
- Improved DOP-PCR (iDOP-PCR): A robust and simple WGA method for efficient amplification of low copy number genomic DNA.PloS one · 2017Article
- The Third International Genomic Medicine Conference (3rd IGMC, 2015): overall activities and outcome highlights.BMC genomics · 2016Article
- Identification of PKD2 mutations in human preimplantation embryos in vitro using a combination of targeted next-generation sequencing and targeted haplotyping.Scientific reports · 2016Article
- Extracellular embryo genomic DNA and its potential for genotyping applications.Future science OA · 2015Article
- Impact of whole-genome amplification on the reliability of pre-transfer cattle embryo breeding value estimates.BMC genomics · 2014Article
- Simultaneous genomic identification and profiling of a single cell using semiconductor-based next generation sequencing.Applied & translational genomics · 2014Article
- Prenatal diagnostic testing of the Noonan syndrome genes in fetuses with abnormal ultrasound findings.European journal of human genetics : EJHG · 2013Article
- DNA methylation: the future of crime scene investigation?Molecular biology reports · 2013Review
- An update of preimplantation genetic diagnosis in gene diseases, chromosomal translocation, and aneuploidy screening.Clinical and experimental reproductive medicine · 2011Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Preimplantation genetic diagnosis (PGD) refers to a procedure for genetically analyzing embryos prior to implantation, improving the chance of conception for patients at high risk of transmitting specific inherited disorders. This method has been widely used for a large number of genetic disorders since the first successful application in the early 1990s. Polymerase chain reaction (PCR) and fluorescent in situ hybridization (FISH) are the two main methods in PGD, but there are some inevitable shortcomings limiting the scope of genetic diagnosis. Fortunately, different whole genome amplification (WGA) techniques have been developed to overcome these problems. Sufficient DNA can be amplified and multiple tasks which need abundant DNA can be performed. Moreover, WGA products can be analyzed as a template for multi-loci and multi-gene during the subsequent DNA analysis. In this review, we will focus on the currently available WGA techniques and their applications, as well as the new technical trends from WGA products.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.