Evidence map›Paper›PMID 21193928›Full record

ArticleParasitology research2011

Zoonotic linkage and variation in Cryptosporidium parvum from patients in the United Kingdom.

Rachel M Chalmers, Richard P Smith, Stephen J Hadfield, Kristin Elwin, Michaela Giles

Abstract read
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In one paragraph

Article in Parasitology research, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Prevalence and Molecular Characterization ofPathogens (Basel, Switzerland) · 2025
    Article
  3. A review of recentCurrent research in parasitology & vector-borne diseases · 2025
    Review
  4. Animals : an open access journal from MDPI · 2024
    Article
  5. Article
  6. Article
  7. Article
  8. Occurrence and Molecular Characterization ofAnimals : an open access journal from MDPI · 2022
    Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Prevalence and Characterization ofFrontiers in veterinary science · 2020
    Article
  16. Prevalence and diversity ofInternational journal for parasitology. Parasites and wildlife · 2019
    Article
  17. International journal for parasitology. Parasites and wildlife · 2019
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Rachel M ChalmersUK Cryptosporidium Reference Unit, Public Health Wales Microbiology, Singleton Hospital, Swansea, SA2 8QA, UK. rachel.chalmers@wales.nhs.uk
Richard P Smith
Stephen J Hadfield
Kristin Elwin
Michaela Giles

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Relationships between patient exposure risks and variation within the Cryptosporidium parvum 60 kDa glycoprotein (GP60) gene were explored in samples isolated from human cases of cryptosporidiosis (n=69) in England and Wales. GP60 family IIa predominated (n=56), followed by IId (n=9). One case was IIc, a newly named genotype IIcA5G3j, and isolates from three cases did not amplify with the GP60 primers. Cases with GP60 family IIa were more likely than IId to have visited a farm, or had contact with farm animals or with their faeces in the 2 weeks prior to illness. Within GP60 family IIa, genotypes IIaA15G2R1 and IIaA17G1R1 predominated (22 cases each); nine other IIa genotypes accounted for 12 cases. The IId genotypes were mainly IIdA17G1 and IIdA18G1 (3 each). Cases with IIaA17G1R1 were particularly linked to zoonotic exposures: visiting a farm or having farm animal contact in the 2 weeks prior to illness. These findings provide further evidence of zoonotic pathways for the transmission of C. parvum isolates.

Indexed as

Polymorphism, GeneticAdolescentAdultAgedAged, 80 and overAnimalsChildChild, PreschoolCryptosporidiosisCryptosporidium parvumDNA PrimersEnglandFemaleGenotypeGlycoproteinsHumansDNA PrimersGlycoproteinsProtozoan Proteins

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.