In mixed hematopoietic chimerism, the donor red cells win.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

20 citing papers in PubMed.

1. Post-Transcriptional Genetic Silencing ofThe New England journal of medicine · 2021
   Trial
2. Low Exposure Busulfan Conditioning to Achieve Sufficient Multilineage Chimerism in Patients with Severe Combined Immunodeficiency.Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation · 2019
   Trial
3. CRISPR-AuNP: physicochemical optimization of a gold nanoparticle platform for cost-effective and modular non-viral gene editing in HSPCs.Gene therapy · 2026
   Article
4. Hematopoietic stem cell therapy with gene modification to treat sickle cell disease.Stem cells translational medicine · 2025
   Review
5. The role of the conditioning regimen for autologous and ex vivo genetically modified hematopoietic stem cell-based therapies: recommendations from the ISCT stem cell engineering committee.Cytotherapy · 2025
   Review
6. A Rare Presentation of Acute Kidney Injury in Diffuse Large B-Cell Lymphoma: A Case Report.Cureus · 2023
   Article
7. Peptide nucleic acid-dependent artifact can lead to false-positive triplex gene editing signals.Proceedings of the National Academy of Sciences of the United States of America · 2021
   Article
8. Unmanipulated Stem Cell Boost for Mixed Chimerism in Transfusion Dependent Thalassemia.Indian journal of hematology & blood transfusion : an official journal of Indian Society of Hematology and Blood Transfusion · 2021
   Article
9. Long-term event-free survival, chimerism and fertility outcomes in 234 patients with sickle-cell anemia younger than 30 years after myeloablative conditioning and matched-sibling transplantation in France.Haematologica · 2020
   Article
10. Genome editing of HBG1 and HBG2 to induce fetal hemoglobin.Blood advances · 2019
    Article
11. Long-term outcome of mixed chimerism after stem cell transplantation for thalassemia major conditioned with busulfan and cyclophosphamide.Bone marrow transplantation · 2018
    Article
12. Hematopoietic Stem Cell Gene Therapy: Progress and Lessons Learned.Cell stem cell · 2017
    Review
13. At least 20% donor myeloid chimerism is necessary to reverse the sickle phenotype after allogeneic HSCT.Blood · 2017
    Article
14. Cure for thalassemia major - from allogeneic hematopoietic stem cell transplantation to gene therapy.Haematologica · 2017
    Review
15. Hematopoietic Stem Cell Transplantation in Adult Sickle Cell Disease: Problems and Solutions.Turkish journal of haematology : official journal of Turkish Society of Haematology · 2015
    Review
16. Correction of the sickle cell disease mutation in human hematopoietic stem/progenitor cells.Blood · 2015
    Article
17. Peripheral red blood cell split chimerism as a consequence of intramedullary selective apoptosis of recipient red blood cells in a case of sickle cell disease.Mediterranean journal of hematology and infectious diseases · 2014
    Article
18. Hematopoietic stem-cell transplantation for sickle cell disease: current evidence and opinions.Therapeutic advances in hematology · 2013
    Article
19. Umbilical cord blood: an evolving stem cell source for sickle cell disease transplants.Stem cells translational medicine · 2013
    Review
20. Split chimerism between nucleated and red blood cells after bone marrow transplantation for haemoglobinopathies.Chimerism · 2011
    Article

Corrections and comments

• Comment on
  Quantitatively different red cell/nucleated cell chimerism in patients with long-term, persistent hematopoietic mixed chimerism after bone marrow transplantation for thalassemia major or sickle cell disease.2011

Authors and funding

3 authors.

Funding

Abstract

PubMed holds no abstract for this paper.

Indexed as