Evidence map›Paper›PMID 21192848›Full record

ArticleEmerging infectious diseases2011

Foodborne illness acquired in the United States--major pathogens.

Elaine Scallan, Robert M Hoekstra, Frederick J Angulo, Robert V Tauxe, Marc-Alain Widdowson, Sharon L Roy, Jeffery L Jones, Patricia M Griffin

Registry-linked trialAbstract read
In one paragraph

Article in Emerging infectious diseases, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06122870 (Double-blind, Placebo-Controlled Trial Assessing the Efficacy and Safety of CampETEC Hyperimmune Bovine Colostrum), which is not on this map. Cited by 2,642 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2,642citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06122870 phase1completednot on this mapstarted 2023, after this paper: background citation

Double-blind, Placebo-Controlled Trial Assessing the Efficacy and Safety of CampETEC Hyperimmune Bovine Colostrum (HBC) for the Prevention of Campylobacter-Mediated Diarrheal Diseases

TypeinterventionalSponsorJohns Hopkins Bloomberg School of Public HealthRan2023 to 2025Enrolled27ConditionsHealthy VolunteerArmsCampETEC HBC product, ProMilk 85, C. jejuni CG8421 Challenge strain
3 · Its place in the literature

Who cites it

2,642 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
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  5. Review
  6. Article
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  9. Seasonality ofApplied and environmental microbiology · 2026
    Article
  10. First Case Report ofInfectious disease reports · 2026
    Article
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  12. Review
  13. Article
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  18. Review
  19. Healthcare costs of foodborne diseases in the United States: an analysis using electronic health records.The European journal of health economics : HEPAC : health economics in prevention and care · 2026
    Article
  20. Article

2,582 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Elaine ScallanCenters for Disease Control and Prevention, Atlanta, Georgia, USA. elaine.scallan@ucdenver.edu
Robert M Hoekstra
Frederick J Angulo
Robert V Tauxe
Marc-Alain Widdowson
Sharon L Roy
Jeffery L Jones
Patricia M Griffin

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Estimates of foodborne illness can be used to direct food safety policy and interventions. We used data from active and passive surveillance and other sources to estimate that each year 31 major pathogens acquired in the United States caused 9.4 million episodes of foodborne illness (90% credible interval [CrI] 6.6-12.7 million), 55,961 hospitalizations (90% CrI 39,534-75,741), and 1,351 deaths (90% CrI 712-2,268). Most (58%) illnesses were caused by norovirus, followed by nontyphoidal Salmonella spp. (11%), Clostridium perfringens (10%), and Campylobacter spp. (9%). Leading causes of hospitalization were nontyphoidal Salmonella spp. (35%), norovirus (26%), Campylobacter spp. (15%), and Toxoplasma gondii (8%). Leading causes of death were nontyphoidal Salmonella spp. (28%), T. gondii (24%), Listeria monocytogenes (19%), and norovirus (11%). These estimates cannot be compared with prior (1999) estimates to assess trends because different methods were used. Additional data and more refined methods can improve future estimates.

Indexed as

Foodborne DiseasesCampylobacterClostridium perfringensFood MicrobiologyFood SafetyHospitalizationHumansNorovirusPopulation SurveillanceSalmonellaToxoplasmaUnited States

Identifiers

PMID21192848
PMCPMC3375761

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.