ArticleMicrobial cell factories2010
Engineering building blocks for self-assembling protein nanoparticles.
Article in Microbial cell factories, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed.
- Multifunctional vesicles in cancer therapy and theranostics: current advances and future challenges.Journal of nanobiotechnology · 2025Review
- Evaluation of beer residual yeast as a substrate for the biotechnological process of hyaluronic acid production.World journal of microbiology & biotechnology · 2025Article
- Aggregation of Albumins under Reductive Radical Stress.International journal of molecular sciences · 2024Article
- Nanotechnology's frontier in combatting infectious and inflammatory diseases: prevention and treatment.Signal transduction and targeted therapy · 2024Review
- Manufacturing of non-viral protein nanocages for biotechnological and biomedical applications.Frontiers in bioengineering and biotechnology · 2023Review
- Nanoparticles-mediated CRISPR-Cas9 gene therapy in inherited retinal diseases: applications, challenges, and emerging opportunities.Journal of nanobiotechnology · 2022Review
- Green synthesis of gold nanoparticles using extracellular metabolites of fish gut microbes and their antimicrobial properties.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2020Article
- Rapid and efficient production of cecropin A antibacterial peptide in Escherichia coli by fusion with a self-aggregating protein.BMC biotechnology · 2018Article
- Engineering protein nanocages as carriers for biomedical applications.NPG Asia materials · 2017Review
- Systems metabolic engineering, industrial biotechnology and microbial cell factories.Microbial cell factories · 2012Article
- Exploitation of marine bacteria for production of gold nanoparticles.Microbial cell factories · 2012Article
- Packaging protein drugs as bacterial inclusion bodies for therapeutic applications.Microbial cell factories · 2012Article
- Intracellular CXCR4⁺ cell targeting with T22-empowered protein-only nanoparticles.International journal of nanomedicine · 2012Article
- Biological activities of histidine-rich peptides; merging biotechnology and nanomedicine.Microbial cell factories · 2011Article
- Self-assembling, protein-based intracellular bacterial organelles: emerging vehicles for encapsulating, targeting and delivering therapeutical cargoes.Microbial cell factories · 2011Review
- Yeast processing bodies and stress granules: self-assembly ribonucleoprotein particles.Microbial cell factories · 2011Article
- Post-production protein stability: trouble beyond the cell factory.Microbial cell factories · 2011Article
- Streamlined protein expression and purification using cleavable self-aggregating tags.Microbial cell factories · 2011Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Like natural viruses, manmade protein cages for drug delivery are to be ideally formed by repetitive subunits with self-assembling properties, mimicking viral functions and molecular organization. Naturally formed nanostructures (such as viruses, flagella or simpler protein oligomers) can be engineered to acquire specific traits of interest in biomedicine, for instance through the addition of cell targeting agents for desired biodistribution and specific delivery of associated drugs. However, fully artificial constructs would be highly desirable regarding finest tuning and adaptation to precise therapeutic purposes. Although engineering of protein assembling is still in its infancy, arising principles and promising strategies of protein manipulation point out the rational construction of nanoscale protein cages as a feasible concept, reachable through conventional recombinant DNA technologies and microbial protein production.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.