Evidence map›Paper›PMID 21192304›Full record

Trial reportSpine2011

Transforaminal epidural clonidine versus corticosteroid for acute lumbosacral radiculopathy due to intervertebral disc herniation.

Abram H Burgher, Bryan C Hoelzer, Darrell R Schroeder, Gregory A Wilson, Marc A Huntoon

Registry-linked trialAbstract readComparative StudyRandomized Controlled Trial
In one paragraph

Trial report in Spine, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00588354 (Pilot Study of Transforaminal Epidural Injection of Clonidine for the Treatment of Acute Lumbosacral Radiculopathy), which is not on this map. Cited by 11 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 4 pooled it
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00588354 naterminatednot on this map

Pilot Study of Transforaminal Epidural Injection of Clonidine for the Treatment of Acute Lumbosacral Radiculopathy

TypeinterventionalSponsorMayo ClinicRan2006 to 2009Enrolled26ConditionsLumbar and Other Intervertebral Disc Disorders With RadiculopathyArmsClonidine, Triamcinolone hexacetonide, Lidocaine HCl
3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 4 syntheses or guidelines pooled it, 31 citations in OpenAlex.

  1. Epidural corticosteroid injections for lumbosacral radicular pain.The Cochrane database of systematic reviews · 2020
    Pooled it
  2. Pooled it
  3. Pooled it
  4. A systematic review and meta-analysis of biological treatments targeting tumour necrosis factor α for sciatica.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2013
    Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Abram H BurgherThe Pain Center of Arizona, Peoria, AZ, USA.
Bryan C Hoelzer
Darrell R Schroeder
Gregory A Wilson
Marc A Huntoon
Mayo Clinic · US

Funding

MAYO CLINIC CENTER FOR TRANSLATIONAL SCIENCE ACTIVITIESUL1RR024150 · NCRR · MAYO CLINIC ROCHESTER · PI RIZZA, ROBERT A. · 2006 to 2011
$66.4M
NCRR NIH HHS UL1 RR024150
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Acute DiseaseAdrenal Cortex HormonesAdultAgedClonidineFemaleHumansInjections, EpiduralIntervertebral Disc DisplacementLumbosacral RegionMaleMiddle AgedPain MeasurementProspective StudiesRadiculopathyTriamcinoloneAdrenal Cortex HormonesClonidineTriamcinolone

Identifiers

PMID21192304
PMCPMC3052879
OpenAlexW2060964066

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.