ArticleWorld journal of gastrointestinal endoscopy2010
Gastroesophageal reflux disease: Important considerations for the older patients.
Article in World journal of gastrointestinal endoscopy, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02274636 (Study of a Dietary Supplement for Reflux During Sleep), which is not on this map. Cited by 35 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Study of a Dietary Supplement for Reflux During Sleep
Who cites it
35 citing papers in PubMed, 1 synthesis or guideline pooled it, 88 citations in OpenAlex.
- Prevalence of Gastroesophageal reflux disease in patients with Idiopathic pulmonary fibrosis: a systematic review and meta-analysis.BMC pulmonary medicine · 2026Pooled it
- GERD in elderly patients: surgical treatment with Nissen-Rossetti laparoscopic technique, outcome.BMC surgery · 2012Trial
- Ineffective Esophageal Motility and Its Predictors in Gastroesophageal Reflux Disease Patients with Pathologic Acid Exposure Time.Journal of neurogastroenterology and motility · 2026Article
- Frailty and osteoporotic fractures represent mutual risks for each other with common physiological backgrounds.JBMR plus · 2025Article
- Evaluation of the Susceptibility of Bangladeshi University Students to Gastroesophageal Reflux Disease (GERD) and Its Associated Factors: A Cross-Sectional Study.Health science reports · 2025Article
- Upper gastrointestinal bleeding differences between older and younger adults: should bleeding in non-cirrhotic patients be considered a geriatric syndrome?Therapeutic advances in gastroenterology · 2025Article
- Understanding the demographic and socioeconomic determinants of morbidity in Eastern Uganda: a retrospective analysis of the Iganga-Mayuge health and demographic surveillance data.BMJ public health · 2024Article
- Pembrolizumab in combination with trastuzumab for treatment of HER2-positive advanced gastric or gastro-esophageal junction cancer.Annals of medicine and surgery (2012) · 2024Review
- Impact of Age on Long-Term Outcomes of Laparoscopic Nissen Fundoplication-A Single Center Study.Medicina (Kaunas, Lithuania) · 2024Article
- Prevalence and risk factors of gastroesophageal reflux disease in Iran: A cross-sectional analysis from the PERSIAN cohort.PloS one · 2024Article
- Predictors of Pathological Gastroesophageal Reflux among Emirati Patients with Reflux Symptoms Who Undergo Wireless pH Monitoring.Middle East journal of digestive diseases · 2023Article
- Exploring patient treatment decision making for osteoarthritis in the UAE: a cross-sectional adaptive choice-based conjoint study.BMC public health · 2023Article
- Atopic dermatitis and risk of gastroesophageal reflux disease: A nationwide population-based study.PloS one · 2023Article
- Aging Combined with High Waist-to-Hip Ratio Is Associated with a Higher Risk of Gastro-Esophageal Reflux Disease.Journal of clinical medicine · 2022Article
- Proanthocyanidins mitigate bile acid-induced changes in GSTT2 levels in a panel of racially diverse patient-derived primary esophageal cell cultures.Molecular carcinogenesis · 2022Article
- Quantitative assessment of multichannel intraluminal impedance pH and its clinical implications.Physiological reports · 2022Article
- Impact of Laparoscopic Sleeve Gastrectomy on Gastroesophageal Reflux Disease and Risk Factors Associated with Its Occurrence Based Upon Quality of Life.Obesity surgery · 2021Article
- Endoscopic Findings of Gastro-Esophageal Reflux Disease in Elderly and Younger Age Groups.Frontiers in medicine · 2021Article
- Quality of Life in Gastroesophageal Reflux Disease Three Months After Laparoscopic Nissen's Fundoplication.Cureus · 2020Article
- Risk assessment of obstructive sleep apnea among gastroesophageal reflux disease patients in Taif, Saudi Arabia.Journal of family medicine and primary care · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Gastroesophageal reflux disease (GERD) is the most common upper gastrointestinal disorder seen in the elderly. The worldwide incidence of GERD is increasing as the incidence of Helicobacter pylori is decreasing. Although elderly patients with GERD have fewer symptoms, their disease is more often severe. They have more esophageal and extraesophageal complications that may be potentially life threatening. Esophageal complications include erosive esophagitis, esophageal stricture, Barrett's esophagus and adenocarcinoma of the esophagus. Extraesophageal complications include atypical chest pain that can simulate angina pectoris; ear, nose, and throat manifestations such as globus sensation, laryngitis, and dental problems; pulmonary problems such as chronic cough, asthma, and pulmonary aspiration. A more aggressive approach may be warranted in the elderly patient, because of the higher incidence of severe complications. Although the evaluation and management of GERD are generally the same in elderly patients as for all adults, there are specific issues of causation, evaluation and treatment that must be considered when dealing with the elderly.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.