ArticleBiophysical journal2011
Near-critical fluctuations and cytoskeleton-assisted phase separation lead to subdiffusion in cell membranes.
Article in Biophysical journal, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
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Who cites it
30 citing papers in PubMed.
- Phase separation across membranes and condensates in cell organization and function.Nature reviews. Molecular cell biology · 2026Review
- Detecting directed motion and confinement in single-particle trajectories using hidden variables.eLife · 2026Article
- Hemoglobin Binding to the Red Blood Cell (RBC) Membrane Is Associated with Decreased Cell Deformability.International journal of molecular sciences · 2024Article
- Yeast cells actively tune their membranes to phase separate at temperatures that scale with growth temperatures.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
- Noncatalytic Bruton's tyrosine kinase activates PLCγThe Journal of biological chemistry · 2020Article
- Imaging FCS delineates subtle heterogeneity in plasma membranes of resting mast cells.Molecular biology of the cell · 2020Article
- Tuning Length Scales of Small Domains in Cell-Derived Membranes and Synthetic Model Membranes.Biophysical journal · 2018Article
- Complex dynamics at the nanoscale in simple biomembranes.Scientific reports · 2017Article
- Effects of soft interactions and bound mobility on diffusion in crowded environments: a model of sticky and slippery obstacles.Physical biology · 2017Article
- The mystery of membrane organization: composition, regulation and roles of lipid rafts.Nature reviews. Molecular cell biology · 2017Review
- Linoleic acid: Is this the key that unlocks the quantum brain? Insights linking broken symmetries in molecular biology, mood disorders and personalistic emergentism.BMC neuroscience · 2017Review
- The Continuing Mystery of Lipid Rafts.Journal of molecular biology · 2016Review
- Functional nanoscale coupling of Lyn kinase with IgE-FcεRI is restricted by the actin cytoskeleton in early antigen-stimulated signaling.Molecular biology of the cell · 2016Article
- Interleaflet Coupling, Pinning, and Leaflet Asymmetry-Major Players in Plasma Membrane Nanodomain Formation.Frontiers in cell and developmental biology · 2016Review
- Anomalous Dynamics of a Lipid Recognition Protein on a Membrane Surface.Scientific reports · 2015Article
- Cholesterol segregates into submicrometric domains at the living erythrocyte membrane: evidence and regulation.Cellular and molecular life sciences : CMLS · 2015Article
- GPI-anchored proteins do not reside in ordered domains in the live cell plasma membrane.Nature communications · 2015Article
- Cytoskeletal pinning controls phase separation in multicomponent lipid membranes.Biophysical journal · 2015Article
- Article
- Raft formation in lipid bilayers coupled to curvature.Biophysical journal · 2014Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We address the relationship between membrane microheterogeneity and anomalous subdiffusion in cell membranes by carrying out Monte Carlo simulations of two-component lipid membranes. We find that near-critical fluctuations in the membrane lead to transient subdiffusion, while membrane-cytoskeleton interaction strongly affects phase separation, enhances subdiffusion, and eventually leads to hop diffusion of lipids. Thus, we present a minimum realistic model for membrane rafts showing the features of both microscopic phase separation and subdiffusion.
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