ArticleCancer causes & control : CCC2011
Temporal trends in the black/white breast cancer case ratio for estrogen receptor status: disparities are historically contingent, not innate.
Article in Cancer causes & control : CCC, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.
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Who cites it
12 citing papers in PubMed, 2 syntheses or guidelines pooled it, 20 citations in OpenAlex.
- Health Inequalities amongst People of African Descent in the Americas, 2005-2017: A Systematic Review of the Literature.International journal of environmental research and public health · 2019Pooled it
- Receptor-defined subtypes of breast cancer in indigenous populations in Africa: a systematic review and meta-analysis.PLoS medicine · 2014Pooled it
- Factors influencing the initiation of adjuvant endocrine therapy in patients with estrogen receptor-positive ductal carcinoma in situ: a single institution experience.Breast cancer research and treatment · 2022Article
- Tumor Specimen Biobanks: Data Gaps for Analyzing Health Inequities-the Case of Breast Cancer.JNCI cancer spectrum · 2018Article
- Associations of Premenopausal Hysterectomy and Oophorectomy With Breast Cancer Among Black and White Women: The Carolina Breast Cancer Study, 1993-2001.American journal of epidemiology · 2016Article
- Population and target considerations for triple-negative breast cancer clinical trials.Biomarkers in medicine · 2013Review
- History, biology, and health inequities: emergent embodied phenotypes and the illustrative case of the breast cancer estrogen receptor.American journal of public health · 2013Article
- Who and what is a "population"? Historical debates, current controversies, and implications for understanding "population health" and rectifying health inequities.The Milbank quarterly · 2012Review
- Age-specific incidence of breast cancer subtypes: understanding the black-white crossover.Journal of the National Cancer Institute · 2012Article
- Occurrence of breast cancer subtypes in adolescent and young adult women.Breast cancer research : BCR · 2012Article
- Disease-free probability after the first primary ductal carcinoma in situ of the breast: a comparison between African-American and White-American women.Breast cancer research and treatment · 2012Article
- Analyzing historical trends in breast cancer biomarker expression: a feasibility study (1947-2009).NPJ breast cancerArticle
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
objectiveFor at least three decades, many investigators have reported on the US black/white breast cancer case ratio for estrogen receptor (ER) status as if it reflected an intrinsic biological difference. In light of racial/ethnic differences in declines in the incidence of ER+ breast cancer, as linked to changing use of hormone therapy, we empirically tested whether the black/white breast cancer estrogen receptor ratio has changed over time.
methodsWe examined temporal trends in the odds of being ER+ among white as compared to black women among all cases of invasive breast cancer occurring among women residing in the catchment area of the SEER 13 Registries Database between 1992 and 2005.
resultsDuring the study period, the odds of being ER+ among the white compared to black cases increased from 1992 to 2002 (a statistically significant joinpoint; p < 0.05; peak odds ratio (2002) = 2.25 (95% confidence interval 2.13, 2.39)). Thereafter, the odds ratio leveled off (post-2002 slope not significantly different from zero; p = 0.326). Among women aged 45-54, moreover, the post-2002 decline tended toward statistical significance (p = 0.0891).
conclusionsThe results suggest the black/white breast cancer case estrogen receptor ratio is historically contingent, not innate.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.