ArticleJournal of materials science. Materials in medicine2011
Magnetically mediated release of ciprofloxacin from polyvinyl alcohol based superparamagnetic nanocomposites.
Article in Journal of materials science. Materials in medicine, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
10 citing papers in PubMed.
- In Situ-Gelling Antimicrobial Poly(oligoethylene glycol methacrylate)-Based Hydrogels Integrating Bound Quaternary Ammonia Compounds and Antibiotic Functionalities for Effective Infected Wound Healing.Advanced healthcare materials · 2025Article
- Hydrogels and Microgels: Driving Revolutionary Innovations in Targeted Drug Delivery, Strengthening Infection Management, and Advancing Tissue Repair and Regeneration.Gels (Basel, Switzerland) · 2025Review
- Advances in preparation and application of antibacterial hydrogels.Journal of nanobiotechnology · 2023Review
- Polymeric Nanocomposites for Environmental and Industrial Applications.International journal of molecular sciences · 2022Review
- Self-Assembled chitosan/phospholipid nanoparticles: from fundamentals to preparation for advanced drug delivery.Drug delivery · 2020Review
- Specialty Tough Hydrogels and Their Biomedical Applications.Advanced healthcare materials · 2020Review
- Antibacterial Hydrogels.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2018Review
- Antimicrobial hydrogels: promising materials for medical application.International journal of nanomedicine · 2018Review
- The antimicrobial activity of nanoparticles: present situation and prospects for the future.International journal of nanomedicine · 2017Review
- Gold-functionalized magnetic nanoparticles restrict growth of Pseudomonas aeruginosa.International journal of nanomedicine · 2014Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Polymer nanocomposites exhibiting superparamagnetic behavior have been recognized as a promising tool to achieve targeted drug delivery using external magnetic field for treating complex diseases like cancers and tumors. The present investigation attempts to design a superparamagnetic nanocomposite which could desirably deliver ciprofloxacin drug by application of varying magnetic field. In order to achieve the proposed objectives, a polymer matrix of polyvinyl alcohol-g-polymethyl methacrylate was prepared by free radical polymerization and iron oxide particles were impregnated by in situ precipitation method. The prepared nanocomposites were characterized by techniques like FTIR, electron microscopy (SEM and TEM) and XRD and magnetization studies were performed to ensure superparamagnetic behavior. The antibiotic drug ciprofloxacin was loaded onto the magnetic nanocomposites and the influence of various factors such as percent loading, chemical composition of the nanocomposite, applied magnetic field, pH of the release medium were investigated on the release profiles of the drug. The chemical integrity of the drug and its antibacterial potential were also studied. The dynamics of the release process was also examined mechanistically.
Indexed as
Identifiers
21188482What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.