ReviewCell adhesion & migration
Interactions of meniscal cells with extracellular matrix molecules: towards the generation of tissue engineered menisci.
Review in Cell adhesion & migration. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed, 2 syntheses or guidelines pooled it, 31 citations in OpenAlex.
- Meniscus Repair and Regeneration: A Systematic Review from a Basic and Translational Science Perspective.Clinics in sports medicine · 2020Pooled it
- Are the Biological and Biomechanical Properties of Meniscal Scaffolds Reflected in Clinical Practice? A Systematic Review of the Literature.International journal of molecular sciences · 2019Pooled it
- Collagen-Based Scaffolds for Meniscal Repair and Regeneration.Journal of tissue engineering and regenerative medicine · 2025Review
- Recent advances in 3D bioprinted cartilage-mimicking constructs for applications in tissue engineering.Materials today. Bio · 2023Review
- Recent Advances in Therapeutic Modalities Against Breast Cancer-Related Lymphedema: Future Epigenetic Landscape.Lymphatic research and biology · 2023Review
- Meniscus Matrix Structural and Biomechanical Evaluation: Age-Dependent Properties in a Swine Model.Bioengineering (Basel, Switzerland) · 2022Article
- Applications and prospects of different functional hydrogels in meniscus repair.Frontiers in bioengineering and biotechnology · 2022Review
- Characterization of Macroporous Polycaprolactone/Silk Fibroin/Gelatin/Ascorbic Acid Composite Scaffolds andCartilage · 2021Article
- Meniscal Regenerative Scaffolds Based on Biopolymers and Polymers: Recent Status and Applications.Frontiers in cell and developmental biology · 2021Review
- Patient-specific meniscus prototype based on 3D bioprinting of human cell-laden scaffold.Bone & joint research · 2019Article
- Metallic nanoparticles reduce the migration of human fibroblasts in vitro.Nanoscale research letters · 2017Article
- Current advances in the development of natural meniscus scaffolds: innovative approaches to decellularization and recellularization.Cell and tissue research · 2017Review
- Meniscus regeneration by 3D printing technologies: Current advances and future perspectives.Journal of tissue engineeringReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Menisci are one of the most commonly injured parts of the knee. Conventional surgical interventions are often associated with a long-term increased risk of osteoarthritis. Meniscal tissue engineering utilizes natural or synthetic matrices as a scaffold to guide tissue repair or regeneration in three dimensions. Studies have shown that a diverse cellular response can be triggered depending on the composition of the surrounding extracellular matrix (ECM) components. As such, attempts have been made to replace or repair meniscus defects using tissue grafts or reconstituted ECM components prepared from a multitude of tissues. This commentary summarizes the most recent data on the response of meniscal cells to ECM components, both in vivo and in vitro, and focuses on their potential roles in meniscal repair and regeneration. We also discuss our recent investigations into the interactions of meniscal cells and a self assembled biomimetic surface composed of meniscal ECM molecules. The biological effects conferred by the biomimetic surface, in terms of cell adhesion, proliferation, gene expression profiles and matrix synthesis, were evaluated. Finally, some suggested directions for future research in this field are outlined.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.