ArticleJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology2011
Partial volume correction incorporating Rb-82 positron range for quantitative myocardial perfusion PET based on systolic-diastolic activity ratios and phantom measurements.
Article in Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed.
- The effect of coronary revascularization on regional myocardial blood flow as assessed by stress positron emission tomography.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2017Trial
- Reproducibility of quantitative myocardial perfusion and coronary flow capacity by positron emission tomography: 3D digital silicon photomultiplier solid state vs. legacy 2D analogue systems for clinical practice and trials.European heart journal. Imaging methods and practice · 2024Article
- Simplified quantification of PET myocardial blood flow: The need for technical standardization.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2020Article
- The utility ofJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2019Article
- Improving PET Quantification of Small Animal [Molecular imaging and biology · 2018Article
- Optimizing quantitative myocardial perfusion by positron emission tomography for guiding CAD management.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2017Article
- Rb-82 PET/CT left ventricular mass-to-volume ratios.The international journal of cardiovascular imaging · 2017Article
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3 authors.
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Abstract
backgroundQuantitative myocardial PET perfusion imaging requires partial volume corrections.
methodsPatients underwent ECG-gated, rest-dipyridamole, myocardial perfusion PET using Rb-82 decay corrected in Bq/cc for diastolic, systolic, and combined whole cycle ungated images. Diastolic partial volume correction relative to systole was determined from the systolic/diastolic activity ratio, systolic partial volume correction from phantom dimensions comparable to systolic LV wall thicknesses and whole heart cycle partial volume correction for ungated images from fractional systolic-diastolic duration for systolic and diastolic partial volume corrections.
resultsFor 264 PET perfusion images from 159 patients (105 rest-stress image pairs, 54 individual rest or stress images), average resting diastolic partial volume correction relative to systole was 1.14 ± 0.04, independent of heart rate and within ±1.8% of stress images (1.16 ± 0.04). Diastolic partial volume corrections combined with those for phantom dimensions comparable to systolic LV wall thickness gave an average whole heart cycle partial volume correction for ungated images of 1.23 for Rb-82 compared to 1.14 if positron range were negligible as for F-18.
conclusionQuantitative myocardial PET perfusion imaging requires partial volume correction, herein demonstrated clinically from systolic/diastolic absolute activity ratios combined with phantom data accounting for Rb-82 positron range.
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