ArticleNanomedicine (London, England)2011
Transferrin-mediated targeting of bacteriophage HK97 nanoparticles into tumor cells.
Article in Nanomedicine (London, England), 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
25 citing papers in PubMed.
- Distinct oral DNA viral signatures in rheumatoid arthritis: a Pilot study.Journal of oral microbiology · 2024Article
- Folic acid functionalization for targeting self-assembled paclitaxel-based nanoparticles.RSC advances · 2022Article
- Modification of a Tumor-Targeting Bacteriophage for Potential Diagnostic Applications.Molecules (Basel, Switzerland) · 2021Article
- Bacteriophages as Therapeutic and Diagnostic Vehicles in Cancer.Pharmaceuticals (Basel, Switzerland) · 2021Review
- Physical, chemical, and synthetic virology: Reprogramming viruses as controllable nanodevices.Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology · 2019Review
- Bacteriophages and phage-inspired nanocarriers for targeted delivery of therapeutic cargos.Advanced drug delivery reviews · 2016Review
- Design of virus-based nanomaterials for medicine, biotechnology, and energy.Chemical Society reviews · 2016Review
- Tobacco mosaic virus-based protein nanoparticles and nanorods for chemotherapy delivery targeting breast cancer.Journal of controlled release : official journal of the Controlled Release Society · 2016Article
- Serum albumin 'camouflage' of plant virus based nanoparticles prevents their antibody recognition and enhances pharmacokinetics.Biomaterials · 2016Article
- Virus-Based Nanoparticles as Versatile Nanomachines.Annual review of virology · 2015Review
- Stealth filaments: Polymer chain length and conformation affect the in vivo fate of PEGylated potato virus X.Acta biomaterialia · 2015Article
- Bacteriophage lambda: Early pioneer and still relevant.Virology · 2015Review
- Nanotechnology for cancer treatment.Nanotechnology reviews · 2015Article
- Plasmonic nanodiamonds: targeted core-shell type nanoparticles for cancer cell thermoablation.Advanced healthcare materials · 2015Article
- Using viruses as nanomedicines.British journal of pharmacology · 2014Review
- A virus capsid-like nanocompartment that stores iron and protects bacteria from oxidative stress.The EMBO journal · 2014Article
- Transient contacts on the exterior of the HK97 procapsid that are essential for capsid assembly.Journal of molecular biology · 2014Article
- Design rules for nanomedical engineering: from physical virology to the applications of virus-based materials in medicine.Journal of biological physics · 2013Review
- Sinomenine hydrochloride enhancement of the inhibitory effects of anti-transferrin receptor antibody-dependent on the COX-2 pathway in human hepatoma cells.Cancer immunology, immunotherapy : CII · 2013Article
- Targeted nanoparticles in imaging: paving the way for personalized medicine in the battle against cancer.Integrative biology : quantitative biosciences from nano to macro · 2013Review
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
aimsNext-generation targeted nanodevices are currently under development for imaging and therapeutic applications. We engineered HK97 viral nanoparticles (VNPs) for tumor cell-specific targeting.
methodsA combination of genetic and chemical engineering methods were developed and applied to generate dual-labeled HK97 cysteine mutant particles displaying transferrin and fluorescent labels. The targeting properties of transferrin-conjugated VNPs were evaluated by in vitro experiments using different cancer cell lines.
resultsWe found that HK97-transferrin formulations were indeed targeted to cancer cells in vitro via the transferrin receptor. These studies highlight the utility and facilitate the further development of HK97-based VNPs.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.