Evidence map›Paper›PMID 21181431›Full record

ReviewJournal of mammary gland biology and neoplasia2010

Stromal mediation of radiation carcinogenesis.

Mary Helen Barcellos-Hoff

Open access · greenAbstract readReview
In one paragraph

Review in Journal of mammary gland biology and neoplasia, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 29 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Pancreatic Tumor Microenvironment Modulation by EphB4-ephrinB2 Inhibition and Radiation Combination.Clinical cancer research : an official journal of the American Association for Cancer Research · 2019
    Article
  5. Article
  6. Review
  7. Review
  8. Article
  9. Article
  10. Article
  11. Benign breast tissue composition in breast cancer patients: association with risk factors, clinical variables, and gene expression.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2014
    Article
  12. Review
  13. Article
  14. The tumor stromal microenvironment as modulator of malignant behavior.Journal of mammary gland biology and neoplasia · 2010
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Mary Helen Barcellos-HoffDepartments of Radiation Oncology and Cell Biology, New York University School of Medicine, 566 First Avenue, New York, NY 10016, USA. MHBarcellos-Hoff@nyumc.org
New York University · US

Funding

Bay Area Breast Cancer &the Environment Research CenterU01ES012801 · NIEHS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI HIATT, ROBERT A · 2003 to 2010
$12.4M
NIEHS NIH HHS U01 ES012801
6 · The paper itself

Abstract

Ionizing radiation is a well-established carcinogen in human breast and rodent mammary gland. This review addresses evidence that radiation elicits the critical stromal context for cancer, affecting not only frequency but the type of cancer. Recent data from the breast tumors of women treated with radiation therapy and the cellular mechanisms evident in experimental models suggest that radiation effects on stromal-epithelial interactions and tissue composition are a major determinant of cancer development.

Indexed as

AnimalsBreast NeoplasmsCell Transformation, NeoplasticEnvironmental ExposureFemaleHumansMammary Neoplasms, ExperimentalNeoplasms, Radiation-InducedStromal Cells

Identifiers

PMID21181431
PMCPMC3068291
OpenAlexW2027785401

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.