ArticleMarine biotechnology (New York, N.Y.)2011
Terpenes from the red alga Sphaerococcus coronopifolius inhibit the settlement of barnacles.
Article in Marine biotechnology (New York, N.Y.), 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed.
- A Chemical Toolbox to Unveil Synthetic Nature-Inspired Antifouling (NIAF) Compounds.Marine drugs · 2024Review
- New Insights on Biological Activities, Chemical Compositions, and Classifications of Marine Actinomycetes Antifouling Agents.Microorganisms · 2023Review
- Virtual Screening of a Library of Naturally Occurring Anthraquinones for Potential Anti-Fouling Agents.Molecules (Basel, Switzerland) · 2023Article
- Modelling Antifouling compounds of Macroalgal Holobionts in Current and Future pH Conditions.Journal of chemical ecology · 2022Article
- Antifouling coating based on biopolymers (PCL/ PLA) and bioactive extract from the sea cucumber Stichopus herrmanni.AMB Express · 2022Article
- Antifouling Activity of Halogenated Compounds Derived from the Red AlgaMarine drugs · 2021Article
- Synthesis and Antifouling Activity Evaluation of Analogs of Bromosphaerol, a Brominated Diterpene Isolated from the Red AlgaMarine drugs · 2021Article
- Antifouling Activity of Meroterpenes Isolated from the Ascidian Aplidium aff. densum.Marine biotechnology (New York, N.Y.) · 2021Article
- Halogenated Diterpenes with In Vitro Antitumor Activity from the Red AlgaMarine drugs · 2019Article
- Evaluation of Antifouling Potential and Ecotoxicity of Secondary Metabolites Derived from Red Algae of the GenusMarine drugs · 2019Article
- From Ecology to Biotechnology, Study of the Defense Strategies of Algae and Halophytes (from Trapani Saltworks, NW Sicily) with a Focus on Antioxidants and Antimicrobial Properties.International journal of molecular sciences · 2019Article
- Minireview: algal natural compounds and extracts as antifoulants.Journal of applied phycology · 2018Review
- Anti-microfouling Activity ofFrontiers in microbiology · 2018Article
- From Marine Origin to Therapeutics: The Antitumor Potential of Marine Algae-Derived Compounds.Frontiers in pharmacology · 2018Review
- Hymerhabdrin A, a novel diterpenoid with antifouling activity from the intertidal sponge Hymerhabdia sp.The Journal of antibiotics · 2017Article
- High cytotoxicity and anti-proliferative activity of algae extracts on an in vitro model of human hepatocellular carcinoma.SpringerPlus · 2016Article
- Antitumor and antimicrobial potential of bromoditerpenes isolated from the red alga, Sphaerococcus coronopifolius.Marine drugs · 2015Article
- Searching for "environmentally-benign" antifouling biocides.International journal of molecular sciences · 2014Article
- Antifouling activity of synthetic alkylpyridinium polymers using the barnacle model.Marine drugs · 2014Article
- Antifouling potentials of eight deep-sea-derived fungi from the South China Sea.Journal of industrial microbiology & biotechnology · 2014Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In this study, we screened eight terpenes isolated from the organic extract of Sphaerococcus coronopifolius for their antifouling activity in order to find possible new sources of non-toxic or less toxic bioactive antifoulants. The anti-settlement activity (EC₅₀) and the degree of toxicity (LC₅₀) of S. coronopifolius metabolites was evaluated using larvae of the cirriped crustacean Amphibalanus (Balanus) amphitrite (cyprids and nauplii) as model organism. For five of eight tested metabolites EC₅₀ was lower than 5 mg/L. The most promising results were observed for bromosphaerol (3), which expressed an EC₅₀ value of 0.23 mg/L, in combination with low toxicity levels (LC₅₀ > 100 mg/L). The therapeutic ratio--an index used to estimate whether settlement inhibition is due to toxicity or other mechanisms--is also calculated and discussed.
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Registered trials
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